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Plenary Session

3.48 The Predictive Value of High Tumor Mutational Burden with Dr. Luc Morris

Plenary Session

Vinay Prasad, MD MPH

Health, Medicine, Policy, Oncology, Science & Medicine

4.7789 Ratings

🗓️ 6 March 2021

⏱️ 62 minutes

🧾️ Download transcript

Summary

Today we interview Dr. Luc Morris of Memorial Sloan Kettering Cancer Center on his new paper out now in JAMA Oncology titled "Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase". Response Rates: doi.org/10.1001/jamaoncol.2020.7684 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Transcript

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0:00.0

Welcome. I'm Dr. Vinay Prasad. I'm a hematologist, oncologist, and I'm associate professor of medicine at the University of California, San Francisco. In my professional life, I see patients, I teach trainees, and I do research in health care policy. This is plenary session.

0:22.9

Plenary session is a podcast at the intersection of medicine, oncology, and health policy,

0:27.5

and you're listening to Season 3. On this week's episode, this week on Plenary Session, I'm joined

0:35.0

by Luke Morris. He's a surgeon, he's a professor at Memorial Sloan Kettering Cancer Center.

0:39.2

He is going to talk about his new paper on tumor mutational burden.

0:43.0

Does it predict who responds to cancer immunotherapy?

0:46.5

Does it vary tumor to tumor?

0:48.6

This is a topic that many of you all may know I'm deeply interested in.

0:52.1

I participated as one side of a two-sided debate

0:55.0

in the annals of oncology last year. And let's see. Let's see what the new data shows. You won't

1:00.8

want to miss this discussion. If you like this podcast and want more content, follow me on

1:07.1

Twitter at Viprasad MDMPH. Check out the YouTube channel, Vinayprasad, MDMPH.

1:14.5

Patreon backers will get access to the slides for lectures I give on plenary session.

1:19.1

Want to hear from us?

1:20.3

Email us your question at plenary session, and I'm joined by Luke Morris.

1:36.3

Luke Morris is a surgeon at Memorial Sloan Kettering Cancer Center.

1:39.7

And I dare say he's a friend of mine.

1:42.9

And he's a friend of the show.

1:44.5

Dr. Morris, I think the truth has come out.

1:48.2

I've admitted something.

1:49.6

So it's a really, it's really a pleasure to have you on this podcast.

1:53.4

Big, yeah, big admirer of the show.

...

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