3.24 KEYNOTE-177 & Mathematic Models for Fighting COVID-19 with Dr. Wesley Pegden

Plenary Session

Vinay Prasad, MD MPH

Health, Medicine, Policy, Oncology, Science & Medicine

4.7 • 789 Ratings

🗓️ 4 December 2020

⏱️ 76 minutes

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Summary

This week we return to our roots of oncology and dissect the recent results from KEYNOTE-177. We also have an in-depth interview with mathematician Dr. Wes Pegden of Carnegie Mellon University on a mathematical approach to the COVID-19 pandemic. KEYNOTE-177: doi.org/0.1056/NEJMoa2017699 COVID-19 Mathematical Model: https://math.cmu.edu/~wes/covid.html Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Transcript

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0:00.0	Welcome. I'm Dr. Vinay Prasad. I'm a hematologist, oncologist, and I'm associate professor of medicine at the University of California, San Francisco. In my professional life, I see patients, I teach trainees, and I do research in health care policy. This is plenary session. Plenary session is a
0:24.0	podcast at the intersection of medicine, oncology, and health policy. And you're listening to
0:28.5	season three on this week's episode. We have Dr. West Pegden and he is an associate professor
0:35.8	of mathematics at Carnegie Mellon University.
0:42.0	He is a self-described rigorous thinker when it comes to SARS Cove 2, and he is going to talk through his thoughts on SARS-Cove 2 in a very, very unique and clever way, and that's why I really
0:47.7	enjoy talking to him.
0:49.3	But first, this is an oncology podcast, and we have not forgotten our roots, and I'm back with an analysis of Keynote 177, which came out on December 3, 2020.
0:57.9	You won't want to miss the discussion.
0:59.6	It is going to be super interesting.
1:02.0	PFS, waterfall plots, missing bars.
1:04.9	You don't want to miss this.
1:06.3	Stay tuned.
1:08.7	If you like this podcast and want more content, follow me on Twitter at
1:12.5	Viprasad MDMPH.
1:15.1	Check out the YouTube channel, Vinayprasad MDMPH.
1:19.3	Patreon backers will get access to the slides for lectures I give on plenary session.
1:23.9	Want to hear from us?
1:25.1	Email us your question at plenary session podcast at gmail.com.
1:37.9	Keynote 177, Pemberlism, Mabin, Microsatellite, instability, high, advanced colorectal cancer.
1:44.3	This is an interesting study.
1:46.7	This is, of course, a randomized control trial against Pembralismab in MSI-high or D-D-D-D-M-M-R tumors
1:53.0	versus chemotherapy.
	...

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