#272: Barbora de Courten, PhD – Effect of Carnosine on Glucose Metabolism and Chronic Disease Risk

Sigma Nutrition Radio

Danny Lennon

Sigma, Dietetics, Evidencebased, Nutrition, Training, Health & Fitness, Science, Diet, Fitness, Evidence, Bodybuilding, Health

4.8 • 626 Ratings

🗓️ 9 March 2019

⏱️ 30 minutes

🔗️ Recording | iTunes | RSS

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Summary

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About This Episode:

Professor Barbora de Courten, MD PhD FRACP MPH is a Professor at Monash University, Australia. She is a National Heart Foundation Future Leader Fellow and a specialist physician with a PhD in epidemiology, extensive training in clinical trials (NIH) and a Master of Public Health (Monash University). She has expertise across the translational research continuum from epidemiology, human mechanistic studies to clinical trials and public health interventions through to practice.

She is passionate about research into holistic approaches to prevention and treatment of chronic diseases by promoting health through safe, low-cost and easily scalable interventions with the potential to have an immediate public health impact to prevent and treat chronic diseases. She believes this will impact not only health of individuals but also be beneficial to our society and environment we live in.

Her vision is to establish new strategies for prevention and management of chronic diseases, specifically obesity, diabetes and cardiovascular disease. Her goal is that her research findings will ultimately translate into treatment guidelines, reduced diabetes and cardiovascular morbidity and mortality and reduced healthcare costs.

In This Episode We Discuss:
--> Mechanisms by which certain behaviours (inactivity, poor diet, smoking, etc.) increase chronic disease risk: inflammation, oxidative stress and advanced glycation (AGE formation).
--> What is carnosine?
--> How might carnosine supplementation reduce risk?
--> Dosage and timing used in trials to date
--> Prof. de Courten’s trial showing improvements in insulin sensitivity and an oral glucose tolerance test
--> As beta-alanine works by increasing muscle carnosine concentration, could it be useful for the health?

Transcript

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0:00.0	Hey everyone, Danny here. Just going to make a quick announcement before we get into today's podcast. I want to let you know that my good friend Martin MacDonald is going to be doing his world tour of seminars starting soon and is going to be presenting in a number of different locations over the next couple of months. He'll be coming to Belfast, Edinburgh, Sydney, Brisbane, Perth and Dubai pretty soon.
0:23.6	Tickets are on sale now until the 15th of March and you can get 10% off your ticket if you're going to go by using the code Sigma 10 when you book your spot.
0:33.6	So these seminars, whilst aimed at a beginner to intermediate level of knowledge,
0:39.4	can be pretty much applied to everyone. And you, everyone going will learn something no matter
0:44.5	where you're at. All information gets referenced as it typically does at Martin McDonald's
0:49.5	seminar. And personally, one thing I know from Martin seminars is that him and his team at Macnutrition
0:56.7	take care of attendees so if you're worried about perhaps going alone or not knowing other people
1:02.1	or having to travel there they're all awesome to facilitate all that type of stuff you'll be able to get
1:07.1	to know other attendees beforehand online as well at the event itself.
1:12.4	If you want more details of that or to go and book your place on any of those seminars,
1:17.0	you can either go to Martin-McDonnell.com slash tour.
1:22.2	So that's Martin-Mackdonald.com slash tour.
1:25.6	Or just see the show notes to this particular episode and I'll link up to it there.
1:29.9	And then remember, just use the code Sigma 10 when you check out and you'll get 10% off your ticket.
1:35.6	And if you're going, enjoy. That is tickets closing on the 15th of March. So get in before then.
1:43.2	And so for any of you going to any of those locations, go do that now. And with that of March so get in before then and so for any of you go into any of those
1:44.6	locations go do that now and with that let's get into today's episode so we So it is quite well established in animal studies that carnivine reduces inflammation
2:11.4	of stress and advanced locations for the very processes we've just been discussing.
2:18.3	And there is good evidence, again, from animal studies that it has effects on diabetes, on
2:27.3	cardiovascular disease, on dementia, and a lot of other chronic conditions and diabetes complications as well.
2:37.0	Hello and welcome to Sigma Nutrition Radio.
2:54.4	I'm your host, as always, Danny Lennon, and we're at episode 272 of the podcast.
	...

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