#271: Prof. John Hawley – Circadian Metabolomics & Time-Restricted Feeding
Sigma Nutrition Radio
Danny Lennon
4.8 • 626 Ratings
🗓️ 4 March 2019
⏱️ 34 minutes
🧾️ Download transcript
Summary
Links:
About This Episode:
Prof. Hawley is Director of the Mary MacKillop Institute for Health at Australian Catholic Universtiy in Melbourne, Australia.
He has published over 220 scientific manuscripts, written over 100 articles for technical journals and has authored numerous book chapters for exercise biochemistry and sports medicine texts.
He is an Associate Editor for Diabetologia and currently sits on the Editorial Boards of many international journals. He is a frequently invited speaker at both National and International scientific meetings.
John’s primary research focus includes the interaction of exercise and diet on the regulation of fat and carbohydrate metabolism, particularly within skeletal muscle, the molecular basis of exercise training adaptation and the cellular bases underlying exercise-induced improvements in insulin action.
In This Episode We Discuss:
--> Current work being done by Prof. Hawley’s lab on circadian metabolomics
Defining the human metabolome and circadian metabolomics
--> Comparative analysis of the circadian metabolome in the serum versus peripheral tissues (i.e., skeletal muscle)
--> Impact of high-fat or high-carb diet on the daily variation in metabolites
--> How dietary intake is a strong zeitgeber for peripheral clocks
--> Tissue-specificity of the human circadian metabolome
--> Time-restricted feeding in animal models and in humans
Transcript
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| 0:00.0 | Hey everyone, Danny here. Just going to make a quick announcement before we get into today's podcast. I want to let you know that my good friend, Martin MacDonald, is going to be doing his world tour of seminars starting soon and is going to be presenting in a number of different locations over the next couple of months. He'll be coming to Belfast, Edinburgh, Sydney, Brisbane, Perth and Dubai pretty soon. |
| 0:23.5 | Tickets are on sale now until the 15th of March and you can get 10% off your ticket if you're going to go by using the code Sigma 10 when you book your spot. |
| 0:34.3 | So these seminars whilst aimed at a beginner to intermediate level of knowledge, |
| 0:39.4 | can be pretty much applied to everyone and you, everyone going will learn something no matter |
| 0:44.5 | where you're at. All information gets referenced as it typically does at Martin McDonald's |
| 0:49.6 | seminar. And personally, one thing I know from Martin's seminars is that him and his team at Mac Nutrition |
| 0:56.8 | take care of attendees so if you're worried about perhaps going alone or not knowing other people |
| 1:02.1 | or having to travel there they're all awesome to facilitate all that type of stuff you'll be able to get |
| 1:07.1 | to know other attendees beforehand online as well at the event itself |
| 1:11.7 | if you want more details of that or to go and book your place on any of those seminars you can |
| 1:17.7 | either go to martin dash macdonald dot com slash tour so that's martin dash macdonald |
| 1:23.7 | dot com slash tour or just see the show notes to this particular episode and I'll link up to it there. |
| 1:29.9 | And then remember, just use the code Sigma 10 when you check out and you'll get 10% off your ticket. |
| 1:35.7 | And if you're going, enjoy. That is tickets closing on the 15th of March. So get in before then. |
| 1:43.3 | And so for any of you going to any of those locations, go do that now. And with that of March so get in before then and so for any of you go into any of those |
| 1:44.7 | locations go do that now and with that let's get into today's episode |
| 1:49.8 | Psehcadian biology works on a 24-hour cycle. |
| 2:04.3 | Normally we can have access to food 24 hours a day around the clock. |
| 2:08.5 | And what this studies in animals have shown quite clearly is that if we restrict the time of feeding, |
| 2:14.6 | in other words, close that window of feeding to about 8 to 10 hours |
| 2:19.5 | a day between your first and last meal. This is associated with better metabolic health |
| 2:24.4 | and certainly weight loss. So in the early study that we did with Evelyn, we were interested |
... |
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