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The Ultimate Human with Gary Brecka

253. Dr. Jessica Shepherd: On Menopause, HRT, and Longevity Tips for Women

The Ultimate Human with Gary Brecka

Gary Brecka

Health & Fitness

4.83.1K Ratings

🗓️ 17 March 2026

⏱️ 82 minutes

🧾️ Download transcript

Summary

Most women spend years dismissing their own symptoms: brain fog, frozen shoulder, mood crashes, vanishing libido, never realizing these aren’t signs of aging, they’re signals of a hormonal shift that begins nearly a decade before menopause hits. Today, I’m with board-certified OB-GYN and menopause expert Dr. Jessica Shepherd to dismantle the myths that have kept millions of women unnecessarily suffering, including the misrepresented WHI study that put hormone therapy off the table for a generation. CLICK HERE TO BECOME GARYS VIP!: ⁠https://bit.ly/4ai0Xwg⁠ Listen to “The Hers Podcast” on all your favorite platforms! YouTube: ⁠https://bit.ly/4shfwbQ⁠  Apple Podcasts: ⁠https://bit.ly/4doq3x2⁠  Get Dr. Jessica Shepherd’s book, “Generation M: Living Well in Perimenopause and Menopause” here: ⁠https://bit.ly/3NGDjmn⁠  Connect with Dr. Jessica Shepherd Website: ⁠https://bit.ly/3Pf6ZHG⁠  YouTube: ⁠https://bit.ly/47La74k⁠  Instagram: ⁠https://bit.ly/3NG17Xu⁠  TikTok: ⁠https://bit.ly/416VYLb⁠  Facebook: ⁠https://bit.ly/4ryjyeE⁠  X.com: ⁠https://bit.ly/4192QaQ⁠  LinkedIn: ⁠https://bit.ly/3Nhrm6x⁠  Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: ⁠http://bit.ly/4kek1ij⁠ AION: “ULTIMATE10” FOR 10% OFF: ⁠https://bit.ly/4h6KHAD⁠ AIRES: "ULTIMATE20 " FOR 20% OFF: ⁠https://bit.ly/4a3Duze⁠ BAJA GOLD: "ULTIMATE10" FOR 10% OFF: ⁠https://bit.ly/3WSBqUa⁠ BODYHEALTH: “ULTIMATE20” FOR 20% OFF: ⁠http://bit.ly/4e5IjsV⁠ CARAWAY: “ULTIMATE” FOR 10% OFF: ⁠https://bit.ly/3Q1VmkC⁠ COLD LIFE: THE ULTIMATE HUMAN PLUNGE: ⁠https://bit.ly/4eULUKp⁠ GENETIC METHYLATION TEST (UK ONLY): ⁠https://bit.ly/48QJJrk⁠ GENETIC TEST (USA ONLY): ⁠⁠https://bit.ly/3Yg1Uk9⁠ GOPUFF: GET YOUR FAVORITE SNACK!: ⁠https://bit.ly/4obIFDC⁠ H2TABS: “ULTIMATE10” FOR 10% OFF: ⁠https://bit.ly/4hMNdgg⁠ HEALF: 10% OFF YOUR ORDER: ⁠https://bit.ly/41HJg6S⁠ PEPTUAL: “TUH10” FOR 10% OFF: ⁠https://bit.ly/4mKxgcn⁠ RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: ⁠https://bit.ly/44fFza0⁠ SNOOZE: LET’S GET TO SLEEP!: ⁠https://bit.ly/4pt1T6V⁠ WHOOP: JOIN & GET 1 FREE MONTH!: ⁠https://bit.ly/3VQ0nzW⁠ Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: ⁠https://bit.ly/3RPQYX8⁠ Podcasts: ⁠https://bit.ly/3RQftU0⁠ Connect with Gary Brecka Instagram: ⁠https://bit.ly/3RPpnFs⁠ TikTok: ⁠https://bit.ly/4coJ8fo⁠ X: ⁠https://bit.ly/3Opc8tf⁠ Facebook: ⁠https://bit.ly/464VA1H⁠ LinkedIn: ⁠https://bit.ly/4hH7Ri2⁠ Website: ⁠https://bit.ly/4eLDbdU⁠ Merch: ⁠https://bit.ly/4aBpOM1⁠ Newsletter: ⁠https://bit.ly/47ejrws⁠ Ask Gary: ⁠https://bit.ly/3PEAJuG⁠ Timestamps 00:00 Intro of Show 04:20 Dr. Jessica Shepherd’s Background 08:03 Perimenopause: Earlier Than You Think 11:35 Early Signs of Menopause 15:24 Dutch Test and Hormone Replacement Therapy 24:06 Ideal Timeframe for Hormone Therapy 26:33 The Invisible Hormone Disruptors 27:23 The Caregiver Syndrome 28:35 Why Autoimmune Disease Targets Women 30:40 What Does a Healthy Immune System Look Like? 34:38 Blood Sugar Monitoring: HbA1c and CGM 41:50 How to Strengthen Women’s Immune System 47:42 Black Maternal Mortality and Systemic Health Gaps 57:23 Dr. Shepherd’s Message to the Administration 58:43 Role of AI in Healthcare 1:01:40 Generation M: The Book Every Woman Needs 1:03:39 Weight Training as a Longevity Non-Negotiable 1:06:10 Dr. Shepherd’s Morning Routine 1:08:13 Creatine for Muscle and Brain Health 1:12:28 Real-World Recovery: Movement, Nutrition, and Supplements 1:17:14 Connect with Dr. Shepherd 1:21:01 What does it mean to you to be an Ultimate Human? Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

We've always idealized medicine as direction in order to give someone what they need to do in order to be their best health.

0:06.9

So why is it that we have the best of research and the best of resources and we're not applying it in the way that people can actually live longer and live well?

0:15.7

The system is very expensive.

0:17.4

And by shifting some of that health care spending to these preventative care, it's almost

0:21.7

keeping people out of the system. We're classically trained as humans to ignore what your body

0:27.9

is telling you until it tells you something where it's catastrophic. This is why there is such a

0:33.8

prevalence of autoimmune disease in women because where does autoimmune prey?

0:38.6

It preys on the week. I am really trying to capture women before they hit menopause to give them

0:43.5

the best building blocks so that at 60, 70, and 80, they are optimized instead of waiting for it to be

0:50.0

a catastrophic fall off the cliff. Especially for the women and for the men that are listening.

0:53.9

Where do they start?

0:55.0

You know, Gary, that is the million dollar question.

0:57.7

Well, I do have several answers.

0:59.3

One is...

1:00.0

What if I told you that 50 million women have unnecessarily suffered for decades because of one

1:18.4

misquoted study? Today's guest is someone I've been trying to get on this podcast for months

1:22.7

because my wife, my team, and this entire community have been demanding it. Dr. Jessica Shepard is a board-certified

1:29.2

OBGYN, menopause expert, minimally invasive gynecologic surgeon, and the founder of modern

1:35.0

meno, a global community empowering women through midlife and beyond. But here's what makes her

1:40.2

different. She didn't stay in the system. She could have kept her head down, made a great living, and played by the rules. Instead, she chose to blow the whistle on her different. She didn't stay in the system. She could have kept her head down, made a great living,

1:45.0

and played by the rules. Instead, she chose to blow the whistle on how women's health has been

1:49.4

catastrophically mismanaged, and she's rewriting the playbook. In this episode, we're tearing down the

...

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