251: The Neuroscience of Addiction: A Game-Changing Approach with Dr. Paul Kenny
The Addicted Mind Podcast
Duane Osterlind, LMFT
4.8 • 621 Ratings
🗓️ 18 September 2023
⏱️ 44 minutes
🧾️ Download transcript
Summary
Today, let’s journey through the realms of neuroscience, addiction research, and the promising future of treatment strategies for substance use disorders. On this episode, Duane speaks with Dr. Paul Kenny, a distinguished figure in neuroscience and addiction research. He unravels his research on signaling cascades in rodents' brains, providing fascinating insights into addiction-like behaviors.
The discussion turns engaging as Paul illuminates his groundbreaking work with certain treatments and their potential role in addressing cravings and motivation in substance use disorders is nothing short of fascinating.
They also steer the conversation towards an area often overlooked, which is the relationship between drugs, addiction, and satiety. Paul dissects how potent drugs like cocaine and heroin trigger extreme pleasure and consequently, substance use disorders. He shares his insights into how the satisfaction derived from drug use and the ritualistic patterns of drug consumption could be altered to reduce dependence.
This episode sheds light on the promising field of addiction research and the need to raise public awareness of the issue. This is a testament to the incredible work being done by Cure Addiction Now. By understanding the brain's role in addiction, we can potentially change the way we approach substance use disorders and find innovative ways to help those struggling with addiction.
In this episode, you will hear:
- Groundbreaking research on addiction treatment
- Exploring medications to control cravings and motivation
- Drugs, addiction, and satiety relationship
- GLP-1 enhancers and their potential to treat drug addiction
- Exploring GLP-1 modulators for addiction treatment
- About Cure Addiction Now
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Supporting Resources:
Cure Addiction Now
Episode Credits
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Transcript
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| 0:00.0 | Hello, everyone. I hope you are having a wonderful day. |
| 0:09.2 | My name is Dwayne Ospland, and this is the Addicted Mind podcast, and we are on to another episode. |
| 0:16.3 | I have a wonderful guest today, Dr. Paul Kenny. |
| 0:18.9 | He is a Ward Coleman Professor, Chair of the Nash Family Department of Neuroscience, and |
| 0:25.7 | a research scientist with cure addiction now, can, a nonprofit that funds groundbreaking |
| 0:31.9 | research to help people overcome substance use disorder. |
| 0:35.3 | Dr. Kenney also serves as the director of the Drug Discovery Institute. |
| 0:39.8 | At the Icon School of Medicine, his multidisciplinary research involves the study of |
| 0:44.1 | behavioral paradigms, physiological analyses, and the molecular underpinnings of neurobehavioral |
| 0:50.5 | disorders. Dr. Kenny is actively investigating the brains of rodents to uncover new |
| 0:55.1 | signaling cascades that may play a role in addiction-like behaviors. His research lab, the Kenny |
| 1:00.3 | Laboratory, is focused on understanding the neurobiological mechanisms of drug addiction, obesity, |
| 1:06.4 | and schizophrenia, with an emphasis on the role of nicotentic acetycholine receptors in these processes. |
| 1:15.1 | They employ a multidisciplinary approach that includes complex behavioral paradigms, |
| 1:20.3 | physiological analyses, and molecular biological techniques. |
| 1:25.2 | Current projects include the utilization of vector-based delivery systems |
| 1:28.6 | to modify gene expression in the brains of rodents to identify novel signaling cascades that may |
| 1:33.6 | play a role in addiction-like behaviors. I was so excited to have Dr. Kenny on this podcast to talk |
| 1:39.8 | about some of his research because in some of this, he's talking about how simiglutides, what you might |
| 1:46.4 | have heard of of like ozempic or govi some of these medications that are gPL1 inhibitors |
| 1:52.8 | might be used to help with substance use disorder through controlling cravings and motivation. |
| 1:57.8 | We go into the science behind that possibility. It's really exciting research. |
... |
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