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The Kris Gethin Podcast

217. More Fat Loss, Less Muscle Loss? This Peptide Could Change the Game

The Kris Gethin Podcast

Kris Gethin

Fitness, Health & Fitness, Nutrition

4.9598 Ratings

🗓️ 24 July 2025

⏱️ 21 minutes

🧾️ Download transcript

Summary

Is GLP-2s the next level in fat loss or just another excuse to skip the work?

In this episode of the Kris Gethin Podcast, I break down the most advanced GLP peptide on the market right now. You'll learn how this dual-action compound hits both GLP-1s and GIP receptors to accelerate fat loss, crush hunger, and improve metabolic function faster than older GLP-1s.

I walk you through the real-world results my clients are seeing: 15 to 22 percent bodyweight drops, better blood sugar control, and renewed energy. But I also pull back the curtain on the downsides. Nausea. Gut issues. Muscle loss. All of it can happen.

You'll discover how to use GLP-2s the right way. I also share a powerful transformation story from a friend who dropped over 130 pounds and built a physique he never thought possible.

This episode gives you the tools to use modern science as fuel for your transformation, not a crutch to avoid effort.

Listen now. Apply what you learn. And stop messing around.

We Also Discuss:

  • 01:27: How GLP-2s work: dual agonist targeting GLP-1s and GIP

  • 03:46: Why GLP-2s outperform GLP-1s in fat loss and blood sugar control

  • 05:52: GLP-2s vs GLP-1s: side-by-side comparison of results and side effects

  • 08:26: The non-negotiables: training, diet, and recovery on GLP peptides

  • 12:41: Real transformation: how one client lost 130 lbs and built muscle

Thank You To our Sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris 

BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/ 

 

Find more from Kris:

Website: https://www.krisgethin.com/ 

Instagram: https://www.instagram.com/krisgethin/ 

Youtube: https://www.youtube.com/krisgethin 

2 Shred: https://www.unmatchedsupps.com/products/2shred

Transcript

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0:00.0

Welcome to the Chris Getten podcast where we dive deep into the science of building a stronger physique,

0:11.9

unlocking the secrets of anti-aging and optimizing your health through cutting edge biohacks,

0:17.6

fitness strategies and mental resilience. I've been a personal trainer for nearly 30 years now and voted the number one transformation

0:25.2

trainer by governing bodies such as PT Academy, bodybuilding.com and trainerize.

0:31.9

I am the co-founder of unmatched supplements, co-founder of the Chris Kathleenethyn Jims franchise, and co-founder of my

0:39.6

online coaching platform, Chris Kethin Coaching, and author of several books. I'm a hybrid athlete,

0:46.2

a natural pro bodybuilder, and I've competed in events such as Iron Man Triathlon, Ultramarathon,

0:52.0

Spartan, and many more. My goal with this podcast is to cut through

0:56.7

the noise of fitness myth, misconceptions, and deliver clear protocols, actual tips, and real

1:04.1

resilience and science to help you optimize your physique, elevate your physical and mental

1:10.4

health span, and, of course, enhance your

1:13.5

life.

1:15.4

Hello, everybody. Chris Gethen here and welcome to another episode of the Chris Gethin podcast.

1:22.9

So back by popular demand, we are talking about GLP's yet again.

1:28.0

Last week, we spoke about the typical and most popular GLP ones, which is like semi-glutide,

1:34.4

your OZempex.

1:35.7

And now we are going to be talking about what a lot of people refer to and a lot of research

1:41.0

companies refer to is a GLP2.

1:48.0

It's not necessarily a typical GLPp2 it is a g lp one however it does have a gip agonist to it as well which a lot of people then do refer this as

1:55.3

a g lp2 or otherwise known as tisepatide or manj. So whether you've heard about this from your doctor,

2:02.9

a friend, or on the news, we'll walk through how it works, its potential, the downsides, how it

2:08.9

stacks up against rivals like semi-glutide, and the next generation drug redaturide, which a lot

...

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