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Nature Podcast

21 November 2019: A new antibiotic from nematode guts, grant funding ‘lotteries’, and butterfly genomes

Nature Podcast

podcast@nature.com

News, Science, Technology

4.5893 Ratings

🗓️ 20 November 2019

⏱️ 19 minutes

🧾️ Download transcript

Summary

This week, an antibiotic that targets hard-to-treat bacteria, and a roundup of the latest science news.


In this episode:


00:49 Discovering darobactin

Researchers looked inside nematode guts and have identified a new antibiotic with some useful properties. Research Article: Imai et al.


05:45 Research Highlights

Using urine as a health metric, and sniffing out book decay with an electronic nose. Research Article: Miller et al.Research Article: Veríssimo et al.


07:54 News Chat

Adding an element of chance to grant funding, a continental butterfly-sequencing project, and tracking endangered animals via traces of their DNA. News: Science funders gamble on grant lotteriesNews: Every butterfly in the United States and Canada now has a genome sequenceNews: Rare bird’s detection highlights promise of ‘environmental DNA’


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Transcript

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0:00.0

Nature.

0:04.3

In a experiment, I don't know yet.

0:06.2

Why is Blight so far?

0:08.1

Like, it sounds so simple.

0:09.3

They had no idea.

0:10.8

But now the data's...

0:12.0

I find this not only refreshing, but at some level astounding.

0:19.9

Nature.

0:21.8

Hi, listeners, Benjamin here.

0:25.6

Bit of a solo mission for me this week, so we've got a slightly shorter show than usual.

0:31.2

Don't worry, though, we've still got the news chat.

0:33.5

That's coming up at the end of the show.

0:35.4

But first, I've got a story about antibiotics and antibiotic

0:39.0

resistance. Now, as I'm sure you're aware, antibiotic resistance is a serious public health issue around the world.

0:57.0

As more disease-causing bacteria evolve resistance to antibiotics, researchers are desperately

1:02.4

searching for sources of new ones to replace them. And they're looking in some pretty wild places,

1:08.6

inside sea sponges, in leaf cuterant colonies, and in sediment

1:12.7

from the deep ocean bed, to name but three. This week in nature, a team of scientists have found

1:18.9

a new antibiotic, and it's made by bacteria of the genus Photorabdas, which have a very particular

1:25.9

ecological niche, as Kim Lewis from Northeastern University in the US

1:30.0

explains. They live in the microbiome or in the gut of nematodes that live in the soil. But it gets

1:37.5

even more niche than that. These nematodes, which are tiny little worms, are parasites that feed on insect larvae,

...

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