21 November 2019: A new antibiotic from nematode guts, grant funding ‘lotteries’, and butterfly genomes
Nature Podcast
podcast@nature.com
4.5 • 893 Ratings
🗓️ 20 November 2019
⏱️ 19 minutes
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Summary
This week, an antibiotic that targets hard-to-treat bacteria, and a roundup of the latest science news.
In this episode:
00:49 Discovering darobactin
Researchers looked inside nematode guts and have identified a new antibiotic with some useful properties. Research Article: Imai et al.
05:45 Research Highlights
Using urine as a health metric, and sniffing out book decay with an electronic nose. Research Article: Miller et al.; Research Article: Veríssimo et al.
07:54 News Chat
Adding an element of chance to grant funding, a continental butterfly-sequencing project, and tracking endangered animals via traces of their DNA. News: Science funders gamble on grant lotteries; News: Every butterfly in the United States and Canada now has a genome sequence; News: Rare bird’s detection highlights promise of ‘environmental DNA’
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Transcript
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| 0:00.0 | Nature. |
| 0:04.3 | In a experiment, I don't know yet. |
| 0:06.2 | Why is Blight so far? |
| 0:08.1 | Like, it sounds so simple. |
| 0:09.3 | They had no idea. |
| 0:10.8 | But now the data's... |
| 0:12.0 | I find this not only refreshing, but at some level astounding. |
| 0:19.9 | Nature. |
| 0:21.8 | Hi, listeners, Benjamin here. |
| 0:25.6 | Bit of a solo mission for me this week, so we've got a slightly shorter show than usual. |
| 0:31.2 | Don't worry, though, we've still got the news chat. |
| 0:33.5 | That's coming up at the end of the show. |
| 0:35.4 | But first, I've got a story about antibiotics and antibiotic |
| 0:39.0 | resistance. Now, as I'm sure you're aware, antibiotic resistance is a serious public health issue around the world. |
| 0:57.0 | As more disease-causing bacteria evolve resistance to antibiotics, researchers are desperately |
| 1:02.4 | searching for sources of new ones to replace them. And they're looking in some pretty wild places, |
| 1:08.6 | inside sea sponges, in leaf cuterant colonies, and in sediment |
| 1:12.7 | from the deep ocean bed, to name but three. This week in nature, a team of scientists have found |
| 1:18.9 | a new antibiotic, and it's made by bacteria of the genus Photorabdas, which have a very particular |
| 1:25.9 | ecological niche, as Kim Lewis from Northeastern University in the US |
| 1:30.0 | explains. They live in the microbiome or in the gut of nematodes that live in the soil. But it gets |
| 1:37.5 | even more niche than that. These nematodes, which are tiny little worms, are parasites that feed on insect larvae, |
... |
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