4.8 • 1K Ratings
🗓️ 15 October 2025
⏱️ 39 minutes
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HRS-AKI vs. other causes of AKI in cirrhosis: What do serum or urine sodium clues, albumin challenges, and shifting diagnostic criteria actually reveal about getting the diagnosis right?
🔹 Sponsor: Oakstone CME
Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP
Timestamps:
(00:57) | Understanding the Pathophysiology of HRS
(03:42) | How Portal Hypertension Traps the Kidneys
(10:32) | Sorting the Differential of AKI in Cirrhosis Beyond HRS
(18:28) | Hyponatremia and Urine Sodium in Advanced Cirrhosis
(24:04) | Official Diagnosis and Evolving Criteria of HRS
(29:30) | Albumin: When It Helps and When to Hold Back
(34:00) | Recap and Future Directions
Tags: CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Nephrology, renal, hepatology, Portal Hypertension, Liver Disease
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| 0:00.0 | Let's talk about balance. Not the mythical kind, but the kind that you actually build day to day. |
| 0:04.7 | That's why I recommend Oakstone CME to my colleagues. It's designed to fit into your routine and not disrupt it. |
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| 0:20.4 | You don't have to carve out time. You just need to hit play. And what's so great is that you're not just earning credits, CME credits, but it's also learning that actually sticks. So you can feel confident in your knowledge and still have time left for other things in your life. So whether you're looking to stay sharp, improve patient care, or just looking at CME off your to-do list and do it without tipping the |
| 0:38.1 | balance, check out oakstone.com forward slash mixab. Use the code core 25 for actually 25% off. |
| 0:45.2 | This is exclusive to core AM listeners. So go to oakstone.com forward slash mkSAP and don't forget |
| 0:51.1 | to use the code core 25. I always found that pathogenesis fascinating as a medical student and resident. |
| 0:58.7 | I always read, like reading about it, how the failure of one organ ended up affecting the kidneys. |
| 1:05.7 | And then I started as a fellow seeing patients and consuls and realized how tough those |
| 1:11.3 | consults were and how my attendants were also struggling. |
| 1:15.4 | And there was just such a high degree of uncertainty, which led me to start reading more |
| 1:20.3 | and more and more about it and became part of my clinical area of interest. |
| 1:24.6 | That's Dr. Juan Carlos Villas and nephrologist at Ockhner Health. |
| 1:29.2 | Hi, I am Juan Carliswicz. |
| 1:31.4 | I am a nephrologist at Oxtrner Health in New Orleans. |
| 1:36.0 | Welcome to the Core I Am Thigh Pearls podcast, bringing you high-yield evidence-based pearls. |
| 1:41.2 | I'm Dr. Shreda Trevedi, and I'm joined by. |
| 1:44.0 | Hi, I am Dr. Noah Markowitz, |
| 1:46.4 | a PGIY3 internal medicine resident at Montefere in the Bronx. Today's episode is all things |
| 1:52.2 | hepatotorrenal syndrome or HRS, aka, and yes, we're going to be referring to hepatarino |
| 1:58.0 | syndrome as HRS. No and I debated about this so much and I was like, no, we have to call it hepatarino syndrome. But now I'm a full convert and a hepaternal is just a mouthful to say. So you're going to be hearing us say HRS a lot. So this will be a two-part episode. Today we'll be talking all about diagnosis of HRS and next week we'll be all about treatment. Let's talk about the five pearls we'll be covering today. |
| 2:19.8 | Remember, the more you test yourself, the deeper your learning gains. |
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