#185 Neutropenia: 5 Pearls Segment

Core IM | Internal Medicine Podcast

Core IM Team

Mental Health, Education, Health & Fitness, Medicine

4.8 • 1K Ratings

🗓️ 13 August 2025

⏱️ 45 minutes

🔗️ Recording | iTunes | RSS

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Summary

How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add MRSA coverages? Only Pseudomonas coverage? When do you add fungal coverage?

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🔹 Transcript & Show Notes

Timestamps:

(02:24) | Approach to Neutropenia & Duffy Null

(11:38) | Dose and duration-dependent neutropenia vs. immune-mediated neutropenia

(19:46) | When do neutrophils recover?

(29:56) | Classifying Neutropenic Fever Syndromes

(29:53) | Strategies for Managing Low-Risk Neutropenic Fever

(33:02) | Antimicrobial Therapy and Duration in Febrile Neutropenia

Tags: CoreIM, Internal Medicine, Oncology, Hematology, Medical Education, Physician Assistant, Nurse Practitioner, Neutropenic Fever Management, Antibiotics

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Transcript

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1:37.9	I have a colleague who based in the UK who as a medical student in the UK had anemia from heavy menstrual periods, very common in
1:46.2	women, and then also has the dacenol phenotype. And so her PCP saw, you know, two cytopenias, a low
1:52.9	neuterphalcout, and referred her to a hematologist, right? And told her that it might be leukemia.
1:58.6	And so she's a stressed out medical student, you know, just
2:01.7	trying to get by and thinking that she had leukemia. That was Dr. Lauren Mertz, a hematologist
	...

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