#18 - Richard Isaacson, M.D.: Alzheimer’s prevention

The Peter Attia Drive

Peter Attia, MD

Health & Fitness, Medicine, Fitness

4.7 • 7.3K Ratings

🗓️ 1 October 2018

⏱️ 144 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this episode, Richard Isaacson, a neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and NewYork-Presbyterian, discusses strategies for staving off Alzheimer’s disease. Richard shares a wealth of insight for people who want to know more about Alzheimer’s and what you can do to help yourself and your loved ones – starting today and continuing throughout the entire lifespan.

We discuss:

Richard’s fun-facts (and alter egos): “bling” phones, Doogie Howser, and DJ Rush [8:00];
Richard’s impetus to focus on Alzheimer’s disease: Uncle Bob [18:20];
Starting an Alzheimer’s Prevention Clinic [27:00];
How Alzheimer’s is diagnosed [30:00];
Short-term memory, processing speed, executive function and how they’re tested [35:45];
Prevention vs reduction of Alzheimer’s [44:00];
What is the prevalence of Alzheimer’s in America? [49:30];
How do people actually die from Alzheimer’s or dementia? [51:30];
How can people do everything right and still get Alzheimer’s? It’s all about AGE [55:15];
The APOE gene [58:15];
Why is the risk of Alzheimer’s higher for women? [1:13:00];
How many different paths lead to Alzheimer’s? [1:15:45];
What role does MTHFR play in Alzheimer’s? [1:19:45];
What are the “ABCs” of Alzheimer’s prevention? [1:26:45];
Baptists, Tauists, Syners, and Apostates [1:36:30];
Concerns with statin use for high-risk patients [1:45:00];
The use of Theracurmin [1:48:45];
What are the five actionable things one can do to reduce the risk for Alzheimer’s today? [1:54:30];
The cognitive reserve [2:14:15]; and
More.

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Transcript

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0:00.0	Hey everyone, welcome to the Peter Atia Drive. I'm your host, Peter Atia.
0:10.0	The drive is a result of my hunger for optimizing performance, health, longevity, critical thinking,
0:15.7	along with a few other obsessions along the way. I've spent the last several years working
0:19.6	with some of the most successful top performing individuals in the world, and this podcast
0:23.8	is my attempt to synthesize what I've learned along the way to help you live a higher quality
0:28.3	and more fulfilling life. If you enjoy this podcast, you can find more information on today's
0:32.5	episode and other topics at peteratiamd.com.
0:41.7	Hey everyone, welcome to this week's episode of the Peter Atia Drive. This week I have the
0:47.5	privilege of interviewing a good friend, a collaborator, and an all-around interesting dude
0:53.4	named Richard Isaacson. Richard is a neurologist who specializes in Alzheimer's disease. He is the
0:59.9	director of the Alzheimer's Prevention Clinic at Cornell here in New York City. His life has been
1:06.1	touched by Alzheimer's disease, and from a very early age, as Richard describes, he felt a calling
1:10.8	to go into neurology. It is clearly his life's work. He's an absolute expert in Alzheimer's disease,
1:17.0	but specifically has chosen to focus his efforts on the prevention of Alzheimer's disease, as opposed to
1:21.9	the treatment of Alzheimer's disease. This puts him in the minority of neurologists.
1:27.8	Professionally, as I said, he's an associate professor of neurology at Cornell Medical College here
1:33.2	in the city. He's also an attending neurologist at New York Presbyterian Hospital. He grew up not
1:38.8	too far from here in Long Island, or thereabouts. One of my favorite little tidbits I learned about him
1:43.8	is he went to a high school called Connick High School, and he was recently named among the most
1:49.6	distinguished alumni. His photo now hangs alongside fellow recipients, Rosie O'Donnell and Bob
1:56.3	Costus, so that's pretty impressive. He's a little bit of a doogie-houser. Started college at 17,
2:01.8	finished medical school at 23. As I think I point out in the podcast, he finished medical school
	...

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