#172 Microplastics and Macro CV Health Problems: Beyond Journal Club on APACHe Study with NEJM Group

Core IM | Internal Medicine Podcast

Core IM Team

Mental Health, Education, Health & Fitness, Medicine

4.8 • 1K Ratings

🗓️ 5 March 2025

⏱️ 35 minutes

🔗️ Recording | iTunes | RSS

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Summary

What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes?

Join us as we tackle these questions and discuss the APAChE study on microplastics and cardiovascular disease on this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.

🔹 Transcript and Show Notes

🔹 Behind The Scenes YouTube Video

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Timestamps:

(02:24) | Introduction to Plastic's Key Players

(07:59) | Bradhill/Observational Work

(10:33) | APAChE Study Deep Dive

(18:03) | Discussion

📢 Special Thanks:

🎙️ Audio Editing: Jerome Reyes

📊 Graphics: Dr. Jimin Hwang

Tags:

CoreIM, Environmental Health, Medical Education, IMCore, Public Health, Clinical Pearls, Physician, Medical Student, Nurse Practitioner, Epidemiology

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Transcript

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0:00.0	Welcome to Beyond Journal Club, a collaboration between CoreI.M and NEJM group.
0:04.9	The goal of Beyond Journal Club is to take landmark clinical trials and put them into context,
0:09.7	telling the story of how we got to where we are and what it means for how we take care of our patients.
0:15.1	I'm Dr. Greg Katz, a cardiologist at NYU.
0:17.7	I'm Dr. Shreda Gervetti, internist at BIDMC.
0:20.4	And I'm Dr. Herleen Marwa, an editorial
0:22.5	fellow at the New England Journal of Medicine and a pediatrician in Boston.
0:26.7	Wait a minute, Harleen. Let me just hype you up for a second and not hopefully embarrass you,
0:30.8	but you carry a few other hats with that. Thanks. Yeah. So I also have a background in climate
0:36.5	change in health, including some work with the United Nations and the White House. Yeah, I just like slip that in there. Kind of a big deal. Yeah. Well, thank you guys. And maybe thematically, I'm really excited because today we're going to be talking about something I care a lot about, microplastics, and we're going to be looking at the Apache
0:54.9	study, or the pollutants in atherosclerotic plaque are cardiovascular events. The study explored
1:00.7	the association between microplastics and cardiovascular outcomes, and it was published in the March 6,
1:06.2	2024 issue of NEJM. This study raised a ton of questions about big picture things like how can we
1:12.9	use observational data to identify important associations that may cause disease. And this
1:18.0	microplastic question is everywhere from the New York Times to the Atlantic to even my
1:22.4	friends group chats that are becoming infiltrated with questions about plastic-free underwear.
1:30.2	Greg, is there there plastic in underwear?
1:33.0	Should I be worrying about the underwear I'm buying for my boys?
1:34.2	Maybe.
1:39.2	I mean, this stuff hits home, not just with our clothing choices, but also about, like, mundane daily questions.
1:40.1	Like, do I need to feel guilty about buying a bottle of water for my kids?
1:43.7	Totally.
	...

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