5 • 644 Ratings
🗓️ 10 October 2023
⏱️ 36 minutes
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In this episode, we review the role and indications of thrombolytics in acute ischemic stroke. The efficacy, safety, administration considerations, and cost between alteplase and tenecteplase are compared and contrasted.
Key Concepts
References
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0:00.0 | Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions. |
0:11.0 | This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy. |
0:17.0 | This podcast contains general information for educational purposes only. This is not professional |
0:22.4 | advice and should not be used in lieu of obtaining advice from a qualified health care provider. |
0:27.2 | And now on to the show. |
0:31.2 | Welcome to Helix Talk episode 172. I'm your co-host Dr. Kane. And I'm Dr. Patel. |
0:36.8 | And the title of today's episode is Battle of the Clot Busters, Altaplase versus Tenectaplace for acute ischemic stroke stroke. |
0:44.7 | So today we're clearly talking about two commonly used drug therapies for acute ischemic stroke management. |
0:51.3 | And Dr. Patel, this has become a really hot topic. |
0:53.7 | Our hospital system has recently |
0:55.5 | actually switched from Altaplase to Tenectaplace, and I'm guessing many other hospital systems are also |
1:01.2 | either making the move or contemplating the move. So based on that, the logical question is, |
1:06.7 | why are we doing this and what do we need to know about this newer drug, Tenectopace for acute ischemic stroke? |
1:12.0 | And I believe this was our listener requested topic. |
1:15.4 | It was. |
1:16.0 | Yeah, we got a request about this. |
1:18.3 | And, you know, for any listener that has their own topic that they would like to know more |
1:22.5 | about, you're welcome to contact us at helixtalk.com or on Twitter at Helix Talk. |
1:29.4 | So really, the nature of today's episode is to talk about what is the difference between altiplase versus tenecta place? Is one more |
1:34.6 | effective? Is one safer? One cheaper. What is the evidence to support tenectoplastapace? Like, |
1:40.6 | clearly there must be some evidence to dethrone the king of Altaplace, which we've had for a really long time. |
1:46.9 | And then really, what do pharmacists and other health care providers need to know about the use of thrombolytics, TPA, and acute ischemic strokes? |
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