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The Peter Attia Drive

#162 - Sarah Hallberg, D.O., M.S.: Challenging the status quo of treating metabolic disease, and a personal journey through a grim cancer diagnosis

The Peter Attia Drive

Peter Attia, MD

Health & Fitness, Medicine, Fitness

4.7 • 7.3K Ratings

🗓️ 17 May 2021

⏱️ 141 minutes

🧾️ Download transcript

Summary

Sarah Hallberg is the Medical Director at Virta Health and a physician who has spent nearly two decades treating patients with obesity and type 2 diabetes. In the first half of this episode, Sarah discusses how she became a huge believer in the efficacy of carbohydrate restriction for the treatment of type 2 diabetes through her research and clinical experience. Sarah challenges the common beliefs about the role of dietary fat and carbohydrate on the plasma makeup of fatty acids and triglycerides. She also expresses the importance of understanding early predictors of metabolic illness—highlighting one particular fatty acid as the most important early predictor—before finishing with a discussion about how doctors might be able to personalize patients’ metabolic management in the future. In the second half of this episode, Sarah tells the personal story of her own lung cancer diagnosis. She talks about dealing with her grief, deciding to continue her work while prioritizing her family, and how she devised a plan to extend her survival as long as possible.

We discuss:

  • How Sarah discovered the profound impact of carbohydrate restriction for reversing obesity and type 2 diabetes [3:15];
  • Prediabetes and metabolic syndrome: prevalence, early signs, and the importance of treating early [16:00];
  • Overview of fatty acids, how they are metabolized, and understanding what you see in a standard blood panel [29:15];
  • The relationship between diet composition and metabolic markers [35:15];
  • Why palmitoleic acid is such an important biomarker [48:15];
  • The best early indicators of metabolic disease [1:00:00];
  • Personalized management of metabolic illness [1:07:00];
  • Sarah’s cancer diagnosis and the beginning of her journey [1:15:15];
  • The emotional impact of a devastating diagnosis [1:27:15];
  • Sarah’s plan to extend survival [1:36:45];
  • Sarah’s aggressive treatment plan [1:47:30];
  • Life-threatening complications and the return of her cancer [1:59:00];
  • Sarah’s reflections on her approach to life with chronic cancer and balancing her time [2:11:00]; and
  • More.

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Transcript

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0:00.0

Hey everyone, welcome to the Drive Podcast.

0:13.0

I'm your host, Peter Atia.

0:14.8

This podcast, my website, and my weekly newsletter, all focus on the goal of translating

0:18.7

the science of longevity into something accessible for everyone.

0:22.4

Our goal is to provide the best content in health and wellness, full stop, and we've assembled

0:27.0

a great team of analysts to make this happen.

0:29.4

If you enjoy this podcast, we've created a membership program that brings you far more

0:33.2

in depth content if you want to take your knowledge of the space to the next level.

0:37.3

At the end of this episode, I'll explain what those benefits are, or if you want to learn

0:41.0

more now, head over to peteratiamd.com forward slash subscribe.

0:46.3

Now without further delay, here's today's episode.

0:49.1

My guess this week is Sarah Halberg.

0:53.4

Sarah is a physician who has spent the better part of two decades focusing on treating

0:58.2

patients first with obesity and ultimately really finding her niche in type two diabetes.

1:04.0

About 10 years ago, she became a huge believer through her clinical experience in the efficacy

1:09.4

of carbohydrate restriction and the treatment of type two diabetes in that lead to her becoming

1:13.7

involved in a company called Verta Health, which I'm an investor in as well.

1:17.8

So I want to disclose that.

1:19.9

In this podcast, we talk really about two completely separate things, each of which is important

1:24.9

in its own right.

1:26.3

In the first part of this podcast, we discuss the role of dietary fat and carbohydrate on

1:33.1

the plasma makeup of fatty acid and triglyceride.

...

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