159 - A Breath of Fresh Air: Big Changes to the 2023 GOLD Guidelines for COPD

HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast

Sean P. Kane, PharmD, BCPS

Health & Fitness, Medications, Rosalindfranklin, Rfums, Pharmacy, Pharmd, Pharmacist, Medicine, Drugs

5 • 644 Ratings

🗓️ 10 January 2023

⏱️ 39 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

In this episode, we highlight important changes to the 2023 GOLD Guidelines for COPD. In particular, we discuss a revision to the GOLD group classification system and the preferred initial therapies in patients with COPD.

Key Concepts

The newest GOLD COPD guidelines now recognize three GOLD groups – “A”, “B”, and “E”. Group “E” (formerly groups C and D) are patients with frequent exacerbations (defined as 2 or more in the past 12 months or 1 exacerbation requiring hospitalization).
For group “E” patients, the preferred initial inhaler regimen is a LABA+LAMA. Triple therapy (LABA+LAMA+ICS) can be considered if blood eosinophils are elevated.
“Triple therapy” (LABA+LAMA+ICS) has gained traction based on the IMPACT and ETHOS trials – this regimen reduced exacerbations and mortality compared to LABA+LAMA and LABA+ICS.
With an exploding market of new COPD inhalers, the role of the pharmacist is even more critical to help identify affordable medications and provide patient education for proper inhaler technique.

References

Global Strategy for Prevention, Diagnosis, and Management of COPD: 2023 Report. Global Initiative for Chronic Obstructive Lung Disease (GOLD). https://goldcopd.org/2023-gold-report-2/
IMPACT study: Lipson DA, Barnhart F, Brealey N, et al. Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD. N Engl J Med. 2018;378(18):1671-1680. doi:10.1056/NEJMoa1713901
ETHOS study: Rabe KF, Martinez FJ, Ferguson GT, et al. Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD. N Engl J Med. 2020;383(1):35-48. doi:10.1056/NEJMoa1916046

Transcript

Click on a timestamp to play from that location

0:00.0	Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions.
0:11.0	This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy.
0:17.0	This podcast contains general information for educational purposes only. This is not professional
0:22.4	advice and should not be used in lieu of obtaining advice from a qualified health care provider.
0:27.2	And now on to the show. Welcome to Helix Talk episode 159. I'm your host, Dr. Kane. And unfortunately,
0:36.1	Dr. Patel is not feeling well. She has lost her voice.
0:39.3	So she is not with us today, but we do have a very special guest with us, who I will introduce in a second.
0:44.3	But the title of today's episode is A Breath of Fresh Air, Big Changes to the
0:49.3	2023 Gold Guidelines for COPD.
0:52.3	And I mentioned our special guest here. So I am excited to introduce
0:57.6	the audience to Dr. Rachel New, who is a faculty member here at Rosalind Franklin University College of
1:02.9	Pharmacy. Dr. New, could you just kind of introduce yourself and tell the audience about who you are?
1:07.9	Sure thing. So my name is Dr. New. I am a clinical assistant professor here at the college.
1:13.8	I have a split position.
1:15.6	So about 70% of the time, I'm actually practicing
1:18.4	as an internal medicine pharmacy specialist
1:20.2	at Advocate Lutheran General Hospital in Park Ridge.
1:22.8	And 30% of the time, I am teaching here at the college,
1:26.3	primarily in the pharmacotherapy classes and
1:29.1	some classes in the pharmacogenomics as well.
1:31.5	And of course we've tapped you for today because you are the lecture who teaches COPD to our
1:36.4	students.
	...

Please login to see the full transcript.

Previous episode | Next episode

Disclaimer: The podcast and artwork embedded on this page are from Sean P. Kane, PharmD, BCPS, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Sean P. Kane, PharmD, BCPS and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.