#149 Asthma Management and the MANDALA Trial: Beyond Journal Club with NEJM Group

Core IM | Internal Medicine Podcast

Core IM Team

Mental Health, Education, Health & Fitness, Medicine

4.8 • 1K Ratings

🗓️ 10 April 2024

⏱️ 35 minutes

🔗️ Recording | iTunes | RSS

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Summary

Should your patients be reaching for albuterol when their asthma flares up? Some of us may have been treating asthma exacerbations incorrectly for many years… What is the right approach? Tune in to the fifth episode of Beyond Journal Club, a new series brought to you by Core IM in collaboration with NEJM Group, to learn about the latest asthma management trials and guidelines, and how to translate them into better patient care.

Show Notes & Transcript

Time Stamps

01:47 Evolving story of asthma management
03:26 Pathophysiology of asthma management
06:01 Key players & terms
08:56 Story of asthma through the decades
17:55 MANDALA Trial

Tags: IMCore, CoreIM, primary care, pulmonary, nurse practitioner, pharmacist, physician assistant, inhalers

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Transcript

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0:00.0	Welcome to the fifth installment of Beyond Journal Club, a collaboration between CoreIM and AnyJM group.
0:05.7	The goal of Beyond Journal Club is to take landmark clinical trials and put them into context telling
0:10.4	us a story of how we got to where we are and what it means for how we take care of patients.
0:15.0	I'm Dr. Schreichrevetti an internist at BIDMC.
0:18.0	And I'm Dr. Greg Katz, a cardiologist at NYU.
0:21.0	Hi, I'm Dr. Julie Barzley.
0:22.7	I'm a general pediatrician at Boston Children's Hospital,
0:25.7	as well as an editorial fellow at the New England Journal of Medicine.
0:29.0	Today, we are talking about asthma,
0:31.5	specifically the Mundala trial, published in the June 2nd,
0:34.8	2022 issue of the New England Journal of Medicine.
0:37.8	I am so glad we're talking about asthma because you think that when a disease is this common,
0:42.5	it means we understand it pretty well.
0:44.4	But I was so surprised as we dug into the background
0:46.8	research for this podcast, I learned that a lot of the traditional teaching
0:50.7	that I was taught and that a lot of my peers will still reference about asthma is just either wrong or simply incomplete.
0:57.0	Yeah, and asthma is a disease I care a lot about, not just because I'm a pediatrician, but because asthma disproportionately impacts racial and ethnic minority groups,
1:06.2	those from lower socioeconomic groups, and those living in areas with more pollution.
1:10.7	Yeah, this is such an important illness for so many reasons.
1:14.0	And so the big picture question that Mandela asked is,
1:16.8	what is the right rescue drug and asthma?
1:19.0	But to understand why that's the question that it was asking,
	...

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