1471 Ophira Eisenberg + news & clips
Stand Up! with Pete Dominick
Pete Dominick
4.9 • 1.2K Ratings
🗓️ 30 October 2025
⏱️ 103 minutes
🧾️ Download transcript
Summary
My conversation with Ophira starts at about 41 minutes after headlines and clips
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Ophira Eisenberg is a Canadian-born standup comedian, writer, and host. She hosted NPR's comedy trivia show Ask Me Another for 9-years, where she interviewed and played silly games with hundreds of celebrities including Sir Patrick Stewart, Awkwafina, Rosie Perez, Yo-Yo Ma, Bob The Drag Queen, Nick Kroll, Chelsea Handler, Jim Gaffigan, Michael C. Hall, and so many others.
As a comic and a parent to a 6-year-old, Ophira is the host of the new comedy podcast Parenting Is A Joke co-produced by iHeart Radio and Pretty Good Friends Productions. The show launches on October 18th.
She can be seen live, regularly headlining across the United States, Canada, and Europe delivering her unique blend of standup and storytelling to a loyal fan base of smart, irreverent comedy lovers. She has appeared at Montreal's Just for Laughs Festival, The New Yorker Festival, The New York Comedy Festival, Moontower Comedy Festival, Bumbershoot, The Nantucket Film Festival, Women in Comedy Festival and more.
Her new comedy album at special Plant-Based Jokes is available on iTunes and is streaming now on YouTube. Lauded as "hilarious, high risk, and an inspiration," Ophira filmed her comedy special Inside Joke, when she was 8½ months pregnant. The show's material revolves around how she told everyone that she was never going to have kids, and then unexpectedly found herself expecting at "an advanced maternal age." Her other comedy albums, Bangs! and As Is
She has appeared on Comedy Central, This Week at The Comedy Cellar, Kevin Hart's LOL Network, HBO's Girls, Gotham Live, The Late Late Show, The Today Show, and VH-1. The New York Times called her a skilled comedian and storyteller with "bleakly stylish" humor. She was also selected as one of New York Magazine's "Top 10 Comics that Funny People Find Funny," and hailed by Forbes.com as one of the most engaging comics working today.
Ophira is a regular host and teller with The Moth and her stories have been featured on The Moth Radio Hour and in two of The Moth's best-selling collections, including the most recent New York Times Bestseller: How To Tell A Story: The Essential Guide to Memorable Storytelling from The Moth.
Ophira's first book, Screw Everyone: Sleeping My Way to Monogamy (Seal Press), is a comedic memoir about her experiments in the field as a single woman, traveling from futon to futon and flask-to-flask, gathering data, hoping to put it all together and build her own perfect Frankenmate. It was optioned for a feature film.
She is also sought after as a brilliant interviewer and moderator, and has interviewed dozens of celebrities, writers, and actors including Neil Gaiman at New York's Town Hall; Jane Curtain, Anne Beatts, Heather Gardner, Sudi Green, Alysia Reiner, Jeanne Tripplehorn, David Crane, Jeffrey Klerik at The Nantucket Film Festival; Eugene Levy, Catherine O'Hara, Daniel Levy and Annie Murphy at the 92nd Street Y; and Nell Scovell and Sloane Crosley at The Mark Twain House.
Originally from Calgary, Alberta, Canada, Ophira graduated with a Cultural Anthropology and Theater degree from McGill University. She now lives in Brooklyn, NY where she is a fixture at New York City's comedy clubs including the Comedy Cellar, Gotham Comedy Club, New York Comedy Club and Carolines, as well as Brooklyn's famed performance venues The Bell House, Union Hall, and Littlefield. She resides with her husband and son where she can regularly be seen drinking a ton of coffee.
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Transcript
Click on a timestamp to play from that location
| 0:00.0 | Trump says I love tariffs. |
| 0:03.1 | Well, I don't. |
| 0:03.8 | He's a fucking idiot. |
| 0:05.2 | He says the Canadian ad was AI. |
| 0:07.9 | Well, guess what isn't AI? |
| 0:09.8 | Me, motherfucker. |
| 0:11.5 | Fuck you and your whack-ass daddy. |
| 0:16.0 | Wow, fake Ronald Reagan sounds really mad to start off the show. |
| 0:20.8 | Hello and welcome. |
| 0:22.6 | Very excited to have you here because I have Ophira Eisenberg back. |
| 0:26.5 | We had an awesome conversation. |
| 0:28.0 | I think you're going to love it. |
| 0:29.0 | If you want to jump to it, it begins at 41 minute. |
| 0:32.1 | But I hope you'll stay because I've got your headlines and a clip show. |
| 0:36.1 | As always, it is a shit show. |
| 0:37.6 | That is coming up. Of course, it's Thursday. This is the Thursday show, and I want to remind you there is a hangout. I'll be hosting my birthday-slash-Hallowing costume hangout. We're a costume. You know, maybe just a hat. It's just a Zoom hangout. So just your top half, if you want. And we will have fun tonight at 8 East very much. |
| 0:57.5 | Looking forward to it. |
| 0:58.8 | Your advice for me on turning 50 and the way forward and all of it. |
| 1:03.1 | If you're a paid subscriber, I hope to see you tonight at this very special hangout. |
| 1:08.2 | And if you're not, go on over to patreon.com slash pete dominic and sign up now. |
| 1:13.8 | Hope to see it tonight at 8 East. |
| 1:15.5 | All right, let's get into the news. |
... |
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