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The Jordan Harbinger Show

1241: Ketamine | Skeptical Sunday

The Jordan Harbinger Show

Jordan Harbinger

Social Sciences, Self-improvement, Entrepreneurship, Talk Radio, Business, Science, Education

4.8 β€’ 12.1K Ratings

πŸ—“οΈ 16 November 2025

⏱️ 50 minutes

🧾️ Download transcript

Summary

From horse tranquilizer to mental health treatment β€” what's the real story about ketamine? Nick Pell breaks it down on Skeptical Sunday!

Welcome to Skeptical Sunday, a special edition of The Jordan Harbinger Show where Jordan and a guest break down a topic that you may have never thought about, open things up, and debunk common misconceptions. This time around, we’re joined by writer and researcher Nick Pell!

Full show notes and resources can be found here: jordanharbinger.com/1241

On This Week's Skeptical Sunday:

  • Ketamine therapy shows promise for treatment-resistant depression, PTSD, and chronic pain, but it's serious medicine requiring proper medical supervision, not a recreational escape or wellness trend.
  • Clinical ketamine treatment involves IV administration with precise dosing, vital monitoring, and trained medical attendants β€” drastically different from recreational use that can cause severe bladder damage and other complications.
  • The rise of telehealth ketamine clinics and mail-order treatments represents a concerning trend β€” proper vetting requires full psych evaluations, bloodwork, and screening by legitimate medical professionals, not vague promises.
  • Recreational ketamine use carries significant addiction potential and health risks, particularly bladder damage from chronic high doses β€” clinical settings minimize these dangers through controlled administration.
  • If you're considering ketamine therapy, start with a therapist and real medical doctor. Look for evidence-based treatment with proper intake procedures, not spa-like "optimization centers" making grandiose claims.
  • Connect with Jordan on Twitter, Instagram, and YouTube. If you have something you'd like us to tackle here on Skeptical Sunday, drop Jordan a line at [email protected] and let him know!

And if you're still game to support us, please leave a review here β€” even one sentence helps!

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Transcript

Click on a timestamp to play from that location

0:00.0

This episode is sponsored in part by Vital Proteins.

0:02.6

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1:11.6

That's audible.com.

1:14.1

UK slash Wondery.

1:20.0

Welcome to Skeptical Sunday.

1:21.6

I'm your host, Jordan Harbinger.

1:23.4

Today I'm here with Skeptical Sunday co-host writer and researcher Nick Pell.

1:27.1

On the Jordan Harbinger show, we decode the stories, secrets, and skills of the world's most fascinating people

1:31.4

and turn their wisdom into practical advice that you can use to impact your own life and those around you.

1:36.9

Our mission is to help you become a better informed, more critical thinker, and during the week,

1:40.9

we have long-form conversations with a variety of amazing folks from spies to CEOs, athletes, authors, thinkers, and performers. On Sundays, though, it's skeptical Sunday. A rotating guest co-host and I or breakdown a topic you may have never thought about and debunk common misconceptions about that topic. Such as, why tipping makes no sense, acupuncture recycling chem trails hypnosis and more and if you're

2:02.5

new to the show or you want to tell your friends about the show i suggest our episode starter packs these are

2:07.4

collections of our favorite episodes on persuasion and negotiation psychology disinformation junk science

2:12.8

crime and cults and more that'll help new listeners get a taste of everything we do here on the show

2:16.6

just visit jordan harbinger dot com slash start or search for us in your Spotify app to get started.

2:22.6

All right.

2:22.8

Now today, you might have seen ads for ketamine on social media.

2:26.3

And if you're like me, you're thinking, isn't that a horse tranquilizer that Raver Kids used back in the 90s?

2:36.2

And while that's true, ketamine is actually doing a lot of work helping people with depression, chronic pain, PTSD, and other

2:40.9

ailments, both physical and psychological, that are resistant to other kinds of treatments.

...

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