5 • 644 Ratings
🗓️ 11 August 2020
⏱️ 47 minutes
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In this episode, we dive into the pharmacology of ACE inhibitors and ARBs, particularly understanding how they assist in preserving renal function in CKD and yet at the same time can harm the kidneys (e.g. cause AKI).
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0:00.0 | Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions. |
0:11.2 | This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy. |
0:17.5 | This podcast contains general information for educational purposes only. |
0:21.5 | This is not professional advice and should not be used in lieu of obtaining advice from a |
0:25.7 | qualified health care provider. |
0:27.3 | And now on to the show. |
0:31.3 | Welcome to Helix Talk episode 117. |
0:34.2 | I'm your co-host, Dr. Kane. |
0:35.6 | And I'm Dr. Patel. |
0:36.7 | And in today's episode, title the Yin and Yang of Ace and Arbs, how do they really help |
0:44.2 | or harm kidneys? |
0:46.2 | We're going to dive more into the pharmacology of the ACE inhibitors, the ARBs, particularly |
0:52.6 | understanding how do they help in preserving the renal function |
0:56.6 | in patients who have SKD or underlying conditions that could eventually lead to CCD. |
1:01.6 | But at the same time, they could actually harm the kidneys and cause something called acute kidney |
1:07.2 | injury or AKI. So Dr. Patel, when I teach pharmacy students in the second year, |
1:13.2 | Hartfeller is one of the first topics that they learn about. |
1:16.2 | And, you know, these students also learn about hypertension about the same time. |
1:20.0 | They learn about aces and ARBs and how we have to monitor renal function and potassium, |
1:24.8 | you know, a week or two after these agents, aces, or arbs are initiated |
1:29.6 | because it can increase your potassium and make your renal function get acutely worse, |
1:34.7 | as you said, called acute kidney injury. Later on in our curriculum, they learn about chronic |
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