#112 ANA (Antinuclear Antibody) Test: 5 Pearls Segment

Core IM | Internal Medicine Podcast

Core IM Team

Mental Health, Education, Health & Fitness, Medicine

4.8 • 1K Ratings

🗓️ 5 October 2022

⏱️ 35 minutes

🔗️ Recording | iTunes | RSS

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Summary

Is a positive ANA always significant? What does the titer mean? Is the pattern of the ANA helpful? What patient histories should you not get an ANA for and which aspects of the history would raise suspicion for autoimmunity? How can you use the physical exam to assess likelihood of autoimmune disease? What is the ddx for a positive ANA?Show notes, Transcript and References: https://www.coreimpodcast.com/2022/10/05/ana-antinuclear-…5-pearls-segment/ (https://www.coreimpodcast.com/2022/10/05/ana-antinuclear-antibody-test-5-pearls-segment/)Get CME-MOC credit with ACP: https://www.acponline.org/cme-moc/cme/internal-medicine-podcasts/core-im (https://www.acponline.org/cme-moc/cme/internal-medicine-podcasts/core-im)Sponsor: Visit www.medmastery.com/coreim (http://www.medmastery.com/coreim) for 15% off on all subscriptions. Discount code: “COREIM”Timestamps:* 01:37 (https://www.coreimpodcast.com/?p=25112#) Pearl 1* 03:54 (https://www.coreimpodcast.com/?p=25112#) Pearl 2* 13:53 (https://www.coreimpodcast.com/?p=25112#) Pearl 3* 18:07 (https://www.coreimpodcast.com/?p=25112#) Pearl 4* 29:30 (https://www.coreimpodcast.com/?p=25112#) Pearl 5Tags: IM Core, CoreIM, autoimmune, joint disease, titers, Raynaud's, lupus, Rheumatology Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Advertising Inquiries: https://redcircle.com/brands Privacy & Opt-Out: https://redcircle.com/privacy

Transcript

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0:00.0	the patient is looking at a positive result and then they've inevitably gone to the internet and looked up
0:06.2	lupus and it creates a lot of anxiety.
0:10.0	That's Dr Beth Jonas, a rheumatologist at UNC.
0:13.0	And welcome to the Core I Am V Perils Podcast,
0:16.0	bringing you high-yield evidence-based pearls.
0:18.0	I'm Dr. Shreuberti, a hospitalist at Beth
0:20.0	at Beth Israel Medical Center, and today I'm joined by...
0:23.0	Hi, I'm Mithu, a rheologist at Duke University.
0:27.0	And hi, I'm Anne-Marie Kumpfer, a hospital set UNC.
0:30.0	And today we'll be talking about one of the more common causes for a rheumatology referral, a positive A&A.
0:35.8	And if you ever wondered whether you should check that A&A or not and what to do with a positive result this episode is for you.
0:42.3	I certainly have some room for
0:44.4	improvement in this area and I promise well it's not gonna be the worst part.
0:48.3	So early into the episode. Sorry I can't resist a good pun.
0:53.0	Okay, so let's get into the purls we'll be covering today.
0:55.5	Test yourself by pausing after each of the five questions.
0:58.2	Remember, the more you test yourself, the deeper your learning games.
1:06.0	Pearl 1, A&A Tider. Is a positive A&A always significant?
1:08.0	What does the Titer mean?
1:10.0	And does the pattern of the A&A help? Hurl 2, the history. What patient histories should we not get an A&A for?
1:24.0	And what patient histories should raise your suspicion for auto immunity? Pearl 3. The Physical Exam. How can you use the physical exam to assess the likelihood of
1:39.8	autoimmune disease? immune disease. What are? Per4, differential for positive A&A?
	...

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