Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions.

This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy.

This podcast contains general information for educational purposes only. This is not professional

advice and should not be used in lieu of obtaining advice from a qualified health care provider.

And now on to the show.

Welcome to Helix Talk episode 82. I'm your co-host Dr. Kane. I'm Dr. Schumann. I'm Dr.

Patel. And I'm Dr. Rahul Deshmuk. This is the very first time I'm your co-host Dr. Kane. I'm Dr. Schumann. I'm Dr. Patel. And I'm Dr. Rahul Deshmuk. This is the very

first time I'm joining a wonderful group of people to discuss a little more about the topic for the day.

Very, very happy to have you. Yeah, so I'm going to kick off today's episode. Really excited to

introduce, let's get heavy Deuterium Substitution as a Pathway for Drug

Design. Again, what we're really going to look at here is the use of deuteration, specifically

involving the medication dutrebenazine, which is when we discussed way back in episode 76,

looking at tardive dyskinesia management. Feature, again, we have our guest here, Dr. Deshmuk, looking from the pharmacy sciences

department at the role of this medication, not just this current medication, but really

as the future holds for drug design and development and some of the new concepts about,

you know, essentially a new paradigm in drug molecules shifting and discovery

for future targets. And I hope to make some contributions to this. Deuterium as a molecule

that is a part of this discussion today, it's not a novel molecule. And as we discuss more,

you'll realize that it's just a heavy isotope of hydrogen and it has a lot of

unique properties that are being currently exploited to see if we can get into some kind of drug

development with it and that's what we'll be discussing and for those listeners who are maybe a little bit

far removed from the pharmacy sciences courses that they took in pharmacy school, I just want to caution you here that this is stuff that is coming out right now.

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