5 • 644 Ratings
🗓️ 15 August 2017
⏱️ 33 minutes
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In this episode, we discuss three "older" antihypertensives that are not preferred first-line therapies: clonidine, methyldopa, and minoxidil. We outline why these agents are not first-line therapies and review their pharmacology and adverse effect profiles.
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0:00.0 | Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions. |
0:11.0 | This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy. |
0:17.0 | This podcast contains general information for educational purposes only. This is not professional |
0:22.5 | advice and should not be used in lieu of obtaining advice from a qualified health care provider. |
0:27.2 | And now on to the show. |
0:31.0 | Welcome to Helix Talk episode 65. I'm your co-host Dr. Kane. I'm Dr. Schumann. |
0:35.7 | And I'm Dr. Patel. In today's episode is entitled Advanced Hypertension Ninja Skills with some of the oldest blood pressure |
0:42.7 | medications. |
0:44.0 | Today we'll be focusing on three blood pressure medications that are still used in clinical |
0:49.0 | practice but are definitely not first line and really what clinicians need to know about |
0:53.6 | these three medications in terms of why they're not on the radar in terms of first line and really what clinicians need to know about these three medications |
0:54.6 | in terms of why they're not on the radar in terms of first line therapies and then also what to |
0:59.2 | know about them particularly in terms of the side effect profile of those medications. |
1:03.0 | So we're going to talk about the clonidine, the metadopa, and monoxidil at the great length. |
1:09.7 | And I think it's important to kind of step back for a second and think about who decides |
1:13.8 | what is the first line anti-hypertensive and what criteria do they use. |
1:17.8 | And if we go back literally two decades, we're looking at 1997, this is when JNC6 came out. |
1:24.2 | We're all the way up to JNC 8 right now. |
1:26.1 | But what did JNC6 tell us about preferred |
1:29.0 | antihypertensis at that time? So what they said is for uncomplicated hypertension, first |
1:33.5 | line therapy there is going to be beta blockers or thyside diuretics. Beta blockers? Yeah, so |
1:38.7 | again, that's a great point. So that's something now that really is with these later guidelines, |
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