Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions.

This podcast is provided by pharmacists and faculty members at Roslyn Franklin University College of Pharmacy.

This podcast contains general information for educational purposes only. This is not professional

advice and should not be used in lieu of obtaining advice from a qualified health care provider.

And now on to the show.

Welcome to Helix Talk episode 55. I'm your co-host Dr. Kane. I'm Dr. Schumann. And I'm Dr. Patel.

And the title of this episode is How Low Can You Go, Blood Pressure Limbo with Sprint?

We'll be talking about the Sprintz trial and using a clinical case finiet to kind of introduce the clinical conundrum of how low should you target for a blood pressure goal for a patient.

All right.

So let's see what we have today. Mr. Wilson,

a 55-year-old male patient with the blood pressure of 139 systolic and 89 of diastolic, who's on lysineapril

20 milligrams daily. He is currently smoking, no coronary artery disease. He does not have diabetes.

His lipid panel is fairly good and he doesn't have any

other post-medical history and that gives us his Framingham, the 10-year risk score, to be about

18%. Just to touch on his Framingham risk very briefly, one of the main factors that this

patient Mr. Wilson has is his age in terms of what contributes to his

Birmingham risk. And that's obviously a non-modifiable risk factor. In terms of modifiable risk

factors, the big one here is going to be smoking cessation. So for now we'll kind of put that

away because we're really trying to focus on blood pressure. And blood pressure is the other

modifiable risk factor that Mr. Wilson has. But overall, looking at JNC8, some of what the standard we've been going by as far as blood pressure,

his blood pressure is actually at the JNC 8 goal of less than 140 over 90.

So the question there is, should we pursue a more aggressive blood pressure goal?

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