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HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast

052 - Drug Mixology and Dangerous Consequences, Part I

HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast

Sean P. Kane, PharmD, BCPS

Health & Fitness, Medications, Rosalindfranklin, Rfums, Pharmacy, Pharmd, Pharmacist, Medicine, Drugs

5644 Ratings

🗓️ 15 November 2016

⏱️ 29 minutes

🧾️ Download transcript

Summary

In this episode, we discuss some of the most important drug interactions, including serotonin syndrome, St. John's wort, statins and CYP inhibitors, and antihypertensive medications with NSAIDs.

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to Helix Talk, an educational podcast for healthcare students and providers covering real-life clinical pearls, professional pharmacy topics, and drug therapy discussions.

0:11.0

This podcast is provided by pharmacists and faculty members at Rosal Franklin University College of Pharmacy.

0:17.0

This podcast contains general information for educational purposes only. This is not professional

0:22.5

advice and should not be used in lieu of obtaining advice from a qualified health care provider.

0:27.2

And now on to the show.

0:31.2

Welcome to Helix Talk episode 52. I'm your co-host Dr. Kane. I'm Dr. Schumann. And I'm Dr.

0:36.4

Patel. So today we're going to talk about

0:38.6

topic that is near and dear to our heart. It's about drug interaction, drug mixology, and

0:43.5

danger of consequences. And because there are so many of these two review and understand and maybe

0:50.1

make recommendation and impact, we have divided into two parts. So let's talk about part one.

0:55.5

And this is really a common area that pharmacists are experts in, in the sense that drug

1:01.1

interactions are very common and also very complex. There's a lot of them. And then probably the

1:06.2

most important role of the pharmacist is to decide how big of a deal is that drug interaction.

1:11.6

You know, if you run a drug interaction check for aspirin, you're going to see a ton of drugs, but much of the time

1:16.5

those interactions aren't clinically relevant, or they just require a little bit more monitoring

1:20.6

versus a never can use, never can combine these two things. So there's a habit, especially if you're

1:25.5

just simply doing it based on a very surface

1:27.6

level report, and everything's going to be black and white of always use or never use. And again,

1:33.6

there's so many shades of gray in here that you really have to get into some of the complex

1:37.0

pharmacology with the individual patient factors and many other things before it's coming up a

1:41.8

one-size-fits-all answer. And I like what you both just said right now, because nowadays with the computerized database,

1:48.4

we have the flag warnings, and there seems to be like a physician warning fatigue going on,

...

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