Howdy folks, welcome back to another round of the Found My Fitness Podcast.

Today's podcast is a spectacular round two podcast with Dr. Walter Longo.

If you missed the first episode featuring Dr. Longo,

throw your podcast player in reverse and grab that episode to also listen to when you get a moment.

That said, this bad boy is totally stand alone so don't go anywhere just yet.

First, the street cred. Dr. Longo is the current director of the Longgevity Institute at the

University of Southern California and is also the director of oncology and Longgevity program

at the Institute of Molecular Oncology Foundation in Milan, Italy.

Walter is, in a word, a giant. Both himself a pioneer in the field of aging and has an extremely

dynamic and prolific publishing history that's moved the field forward. Many scientists can spend

most of their career working only in one animal model. His work, however, is profoundly translational,

ranging from yeast to rodent and back to where it actually counts to the clinic.

In this episode, he takes us on a journey or a voyage, if you will, back to where it all began

with caloric restriction. Caloric restriction has long been the focus of promising aging

research and research into the amelioration of age-related diseases. Research in animals has

shown impressive results with studies in mice and rats showing chronic caloric restriction

in able to extend the lifespan up to 40%. Also showing the ability in some animal studies to

virtually eliminate type 2 diabetes and dramatically reduce cancer incidents.

Chronic caloric restriction, perhaps unsurprisingly, is not wholly without undesirable qualities,

such as slowed wound healing and a weakened immune system and other related effects.

Not to mention being notoriously hard to practice with long-term caloric restrictions ultimately

failing at reproducing some of the cellular ceiling changes that seem to be important.

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