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Almost all humans experience pain in some form or another during their lives.

And for many folks, pain is a frequent or even constant companion.

A National Institutes of Health Study published last year

reported that about 21% of U.S. adults experienced chronic pain in 2020.

And while there are many medications out there to help

people cope with pain, they can often cause their own headaches, to say the very least.

Now a pharmaceutical company is potentially on the cusp of releasing a brand new type of pain

medication, one that works to block pain signals like opioids do,

but without impacting the brain or spinal cord in ways that can lead to addiction.

For science quickly, I'm Rachel Feltman.

I'm joined today by Marla Broadfoot,

a freelance science journalist who recently covered the new drug for Scientific American.

Marla, thank you so much for joining us today. Happy to be here. So let's start with a pretty basic question, though I think

kind of a complicated one too. When we talk about pain, what is it physiologically? Yeah, that's a

great question. So pain is an unpleasant sensation,

often an extremely unpleasant sensation, that is typically there to tell us that there's something

wrong with your body. But then we feel pain in cases of chronic pain where there isn't

...