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slash UK slash AI for people. Almost all humans experience pain in some form or another during their

lives. And for many folks, pain is a frequent or even

constant companion. A National Institutes of Health Study published last year reported that about 21%

of U.S. adults experienced chronic pain in 2020. And while there are many medications out there to help people cope with pain,

they can often cause their own headaches, to say the very least. Now a pharmaceutical company

is potentially on the cusp of releasing a brand new type of pain medication, one that works to

block pain signals like opioids do, but without impacting the brain or spinal cord

in ways that can lead to addiction. For science quickly, I'm Rachel Feltman. I'm joined today by

Marla Broadfoot, a freelance science journalist who recently covered the new drug for Scientific American.

Marla, thank you so much for joining us today. Happy to be here.

So let's start with a pretty basic question, though I think kind of a complicated one too.

When we talk about pain, what is it physiologically? Yeah, that's a great question. So pain is an

unpleasant sensation, often an extremely unpleasant sensation, that is typically there to tell us that there's something wrong with your body. But then we feel pain in cases of chronic pain where there isn't anything wrong. And so physiologically speaking, our body is home to lots and lots of these

pain sensing nerve cells that act like an alarm system. So they'll detect danger in the form of

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