Your Brain on Ketones: The New Science Linking Metabolic Health, Mental Health, and the Power of Ketosis with Dr. Georgia Ede

The Resetter Podcast with Dr. Mindy

Dr. Mindy Pelz

Alternative Health, Health & Fitness, Science

4.7 • 1.4K Ratings

🗓️ 8 April 2026

⏱️ 74 minutes

🔗️ Recording | iTunes | RSS

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Summary

People with pre-diabetes are 2.7 times more likely to develop major depression. People with new bipolar disorder are 3.5 times more likely to have metabolic syndrome. If that stopped you in your tracks, good – it stopped me too.

I brought Dr. Georgia Ede back to The Resetter Podcast to dig into her new expert consensus on ketogenic diets and mental health, and this conversation is one every woman needs to hear.

Dr. Ede is a Harvard-trained psychiatrist and one of the world's leading experts in nutritional and metabolic psychiatry. What she laid out in this episode completely reframed how I think about brain health, brain energy, and what it actually means to feed your mind.

We get into why the brain is a hybrid engine that runs best on a mixture of glucose and ketones and what happens when it runs on glucose alone. If you've ever wondered whether what you eat is affecting how you think, feel, and function – this one will give you the science and tools to find out.

For more resources related to today's episode, visit the podcast episode page: https://www.drmindypelz.com/ep334

CONNECT WITH DR. GEORGIA EDE:

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Disclaimer: This podcast is intended for educational and informational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making changes to your diet, fasting routine, or lifestyle.

Transcript

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0:00.0	On this episode of The Resetter podcast, I bring you back Dr. Georgia Eaddy.
0:08.3	So if you didn't hear her the first time, you're definitely going to want to hear her this time
0:13.2	because Georgia is a globally recognized expert in nutritional and metabolic psychiatry. Her 25 plus years of clinical experience includes
0:25.9	seven years at Harvard University, where she was the first psychiatrist to offer nutrition-based
0:32.1	approaches to mental health conditions. She is also co-authored, and you're going to hear about this in this episode,
0:39.9	the first inpatient study of the ketogenic diet for serious mental illness. And why I brought
0:47.8	her back to you is twofold. One, so many of you are seeing a positive result when you go into ketosis with your mental health.
0:59.0	Not just brain clarity, but depression, anxiety, focus.
1:06.0	It's like a miracle.
1:08.0	Just overnight, when you get into ketosis, you start to experience your brain
1:13.0	in a different way. And so much of what we have chat about here in my books on my YouTube
1:20.2	channel is we think of fasting and ketosis as a tool for weight loss. And yes, it's phenomenal for that. But what I wanted to bring Georgia
1:29.9	back for is to talk about how it's a tool for mental health. There is a new expert consensus
1:37.9	that she has published with some colleagues, which as you will hear are the protocols.
1:44.2	I know how much you all love protocols.
1:46.5	The protocols for ketosis to help mental health.
1:52.4	And you'll hear in this episode, there was a reason they wanted to do this is they were
1:56.4	finding the ketogenic diet.
1:58.8	And when she says ketogenic diet, by the way,
2:01.0	you'll hear us flip in between fasting as a tool
2:04.9	to get into the ketogenic diet and low carb
2:08.7	as a tool to get into the ketogenic state.
	...

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