Women, Menopause and Alzheimer’s: XX Brain Connections with Lisa Mosconi, Ph.D. : 675

The Human Upgrade with Dave Asprey

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.6 • 7.3K Ratings

🗓️ 10 March 2020

⏱️ 63 minutes

🔗️ Recording | iTunes | RSS

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Summary

My guest today is a neuroscientist and neuro-nutritionist recognized and respected for her contributions to the fields of brain science, the microbiome, and nutritional genomics.

Dr. Lisa Mosconi is the founder and director of the Women's Brain Initiative and associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College in New York. She’s also an associate professor of neuroscience in neurology and radiology at Weill Cornell and an adjunct faculty member at New York University’s Department of Psychiatry.

Her current scientific work focuses on the early detection of Alzheimer’s disease in at-risk people, particularly women. More than a decade of research has shown two things, Dr. Mosconi says: “No. 1, Alzheimer's Disease is not a disease of old age, but rather the disease starts with negative changes in the brain years—if not decades—before any clinical symptoms emerge. So, we're looking at midlife, rather than when you're 70 or 80. No. 2, women tend to develop these negative changes in their brains before men do, and specifically as women go through menopause. That was a big finding.”

“Menopause symptoms don't start in the ovaries,” she says, “they start in the brain.” That’s why Dr. Mosconi uses brain imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI).

She is passionately interested in how risk of memory loss and Alzheimer’s disease can be mitigated, if not prevented, through the combination of appropriate medical care and lifestyle modifications involving diet, nutrition, physical and intellectual fitness. She details this in her new book, “The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease.”

Dr. Mosconi’s research into women’s neurological health is changing the way science approaches the female brain.

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Transcript

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0:00.0	You know, 850 million women have just entered or are about to enter men's
0:08.3	point. That's globally. That's globally, yes. Okay, got it. For many of them, it's an
0:13.5	incredibly confusing, upsetting, and potentially enraging time with their
0:19.3	lives because they need help and they don't really know where to go for help.
0:23.8	You know, you can go on the internet and then you end up with a back full of
0:27.4	supplements that don't necessarily help you. And we should go to your doctor
0:31.5	and they're just like, yeah, you know, it's just a couple of years trying
0:35.0	maybe get a patch or try this lotion, but there's more at the time to go.
0:45.4	Bulletproof Radio, a state of high performance. You're listening to Bulletproof
0:51.1	Radio with Dave Asprey. I was grabbing a danger coffee with my friend the other day
0:56.4	and out of the blue, he said, Dave, what do you do for your skin? I left it
1:00.6	first because it's not like I have a complex skin care routine. But I do know
1:04.3	that my skin is the largest organ in my body and it is the first line of defense
1:09.6	against the world. And it's really permeable if you don't take care of it. So I
1:13.6	do take care of my skin. And one of the few things that I found that works
1:16.6	noticeably is timelines skin health line. That's because timeline uses a
1:21.6	fascinating new ingredient that invented called mydo pure that you've heard
1:25.6	about on the show. It's clinically improvement to support your cell's ability
1:30.3	to make energy. So you have healthier younger looking skin, which takes energy.
1:35.0	One of the things that makes timeline stand out to me is that there are lots
1:38.2	of rigorous clinical trials showing that it works systemically and it works
1:42.3	specifically on your skin. It's made a big difference in how my skin looks
	...

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