Where Our Emotions Come From and How to Hack Them (w/ Lisa Feldman Barrett) and Tarantula Venom Could Be an Opioid Alternative

Curiosity Weekly

Warner Bros. Discovery

Self-improvement, Science, Astronomy, Education

4.6 • 935 Ratings

🗓️ 14 May 2020

⏱️ 11 minutes

🔗️ Recording | iTunes | RSS

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Summary

Learn about where your emotions come from and how you can hack them, with help from psychology researcher and neuroscientist Lisa Feldman Barrett. Plus: learn why tarantula venom could be an alternative to opioids.

Maybe tarantula venom could be an alternative to opioids by Cameron Duke

Agwa, A. J., Tran, P., Mueller, A., Tran, H. N. T., Deuis, J. R., Israel, M. R., McMahon, K. L., Craik, D. J., Vetter, I., & Schroeder, C. I. (2020). Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7. Journal of Biological Chemistry, 295(15), 5067–5080. https://doi.org/10.1074/jbc.ra119.012281
Spider venom key to pain relief without side-effects. (2020). EurekAlert! https://www.eurekalert.org/pub_releases/2020-04/uoq-svk041320.php
Viviane Richter. (2016, February 29). The tarantula’s bite that could stop pain. Cosmosmagazine.com; Cosmos Magazine. https://cosmosmagazine.com/biology/tarantulas-bite-could-stop-pain
Understanding the Epidemic. (2019). CDC.gov; Centers for Disease Control and Prevention. https://www.cdc.gov/drugoverdose/epidemic/index.html

Additional resources from Lisa Feldman Barrett:

Watch our full, uncut interview with Lisa Feldman Barrett from the American Association for the Advancement of Science Annual Meeting (#AAASmtg) on YouTube https://youtu.be/MY0ZqmBzd4g
Pick up “How Emotions Are Made: The Secret Life of the Brain” on Amazon https://amazon.com
Official website https://lisafeldmanbarrett.com/
You aren’t at the mercy of your emotions (TED Talk) https://www.ted.com/talks/lisa_feldman_barrett_you_aren_t_at_the_mercy_of_your_emotions_your_brain_creates_them
Follow @LFeldmanBarrett on Twitter https://twitter.com/LFeldmanBarrett
Other publications by Lisa Feldman Barrett https://amazon.com
Citation for test anxiety study: Jamieson, J. P., Peters, B. J., Greenwood, E. J., & Altose, A. J. (2016). Reappraising Stress Arousal Improves Performance and Reduces Evaluation Anxiety in Classroom Exam Situations. Social Psychological and Personality Science, 7(6), 579–587. https://doi.org/10.1177/1948550616644656

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Transcript

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0:00.0	Hi, you're about to get smarter in just a few minutes with Curiosity Daily from Curiosity.com.
0:06.2	I'm Cody Goff. And I'm Ashley Hamer.
0:08.3	Today you'll learn about why Tarantula Venom could be an alternative to opioids.
0:12.4	Then you'll learn about where your emotions
0:14.2	come from and how to hack them from neuroscientist Lisa Feldman Barrett.
0:17.7	But it satisfies some curiosity.
0:19.4	Even if you aren't afraid of spiders, you still wouldn't want one to bite you.
0:23.8	Those bites hurt. So what if I told you, Spider venom, could be used to cure pain?
0:30.1	Yep, it turns out that certain molecules found in tarantula venom might one day be used as an alternative to opioid painkillers.
0:38.0	Here's why.
0:39.0	When a tarantula catches its prey, it paralyzes its victim by injecting a cocktail of small proteins called peptides.
0:47.0	These peptides are attracted to little gateways on the membranes that surround nerve cells called sodium ion channels.
0:54.8	Nerve cells use these channels to send messages to and from the brain.
0:59.0	If they're blocked by spider venom peptides, then the nerve can't fire and the victim can't move.
1:04.0	Scary, right?
1:06.0	The venom a tarantula produces contains variations on these ion channel blocking peptides
1:11.0	for different types of nerves. This is important because each
1:14.8	nerve pathway is a one-way street that goes either to or from the brain. Motor nerves
1:20.7	are responsible for sending messages from the brain to muscles, telling them to run, jump, or put down the ice cream.
1:26.5	But other types of nerves send sensory information from the body to the brain, such as information about temperature, pressure, or pain.
1:35.0	At the University of Queensland, molecular biologists discovered that a super venomous
1:39.7	tarantula called the Chinese bird spider produces a toxin called huenotoxin 4 that has a special attraction to the ion channels on pain receptors.
	...

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