Today, we return with a full review of treatments for ADHD and bipolar disorder.

Welcome to the Carlythe Psychiatry Podcast, keeping psychiatry honest since 2003.

I'm Chris Aiken, the editor-in-chief of the Carlatte Psychiatry Report.

And I'm Kelly Newsom, a psychiatric MP, and a dedicated reader of every issue.

Last week, you learned that the stimulants, methamphetamines, are often used for cognitive

problems in ADHD and bipolar disorder.

Despite a real lack of evidence supporting them, despite animal models

where they're used to worsen bipolar or cause bipolar, and despite other risks like

mania, psychosis, and neurotoxicity. So we recommended that if you're going to use a

stimulant, try to use methylphenidate in place

of amphetamine and bipolar.

It's less risky.

And try to keep the doses low, because those problems we mentioned are dose-dependent.

We then went on to list my top treatments for bipolar and ADHD, because there are two treatments

that don't harm the brain and that treat both illnesses. Those are armadaphanil for bipolar

depression and for ADHD, or clonidine, which treats bipolar mania and ADHD.

But there are many other options that you might consider.

Let's get into them today, starting with those other non-stimulants that have an antidepressant-like

structure.

The other FDA-approved non-stimulants are admoxatine, stratera, and viloxazine, Quelberry.

But these are controversial in bipolar disorder because they have antidepressant structures.

Both are known to induce mania, and while admoxatine failed to gain approval as an antidepressant,

...