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Locked On 49ers - Daily Podcast On The San Francisco 49ers

WEEK 4 CLASH: Can the 49ers Overcome DEVASTATING Nick Bosa Injury vs Jaguars?

Locked On 49ers - Daily Podcast On The San Francisco 49ers

Locked On Podcast Network

Daily Podcast, San Francisco Nfl, San Francisco 49ers, Bay Area Football, Nfl, 49ers, San Francisco Football, Sourdough Sam, Bay Area Nfl, San Francisco, Niners, 49ers Highlights, 49ers Football, 49ers News, Sports, Sports Podcast, 49ers Game, Football, 49ers Today, 49ers Nfl, 49ers Podcast, Podcast, Bay Area

4.61K Ratings

🗓️ 25 September 2025

⏱️ 33 minutes

🧾️ Download transcript

Summary

49ers vs Jaguars: Clash of Titans or Battle of Attrition? San Francisco 49ers face a crucial test against the Jacksonville Jaguars in Week 4. With Nick Bosa sidelined, can the 49ers' defense hold strong? Christian McCaffrey's explosive potential clashes with Trevor Lawrence's quest for consistency. Locked On hosts Brian Peacock and Tony Wiggins break down key matchups, dissect game-changing strategies, and offer insider perspectives on this high-stakes showdown.

Transcript

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0:00.0

Week four is upon a San Francisco 49ers hosting the Jacksonville Jaguars.

0:05.0

Only one loss between these teams.

0:08.3

It's crossover time in week four right now.

0:17.6

You are locked on NFL crossover.

0:26.5

Part of the Locked on Podcast Network, your team every day.

0:35.2

Welcome to another Locked on podcast network crossover episode week four. It is the Jacksonville Jaguars at the San Francisco 49ers.

0:38.1

I am the host of Lockdown 49ers, Brian Peacock, along with Tony Wiggins, the host of Lockedon Jaguars.

0:44.2

We're going to be breaking down the biggest storylines, key matchups, and the paths to victory for each team in week four, which should be a really good one.

0:53.2

This episode, as all crossover episodes are on

0:56.2

the Lockdown Network brought to you by Price Picks. Download the Price Picks app today and use

1:00.8

code. Locked on NFL, we get $50 in lineups after you play your first $5 lineup.

1:07.4

Whig, it's been a little bit. How are you doing, man? I'm excited for this one.

1:11.3

And I'm excited to hear about what the biggest storyline is right now in Jacksonville,

1:17.0

heading into a week four matchup against the San Francisco 40.

1:20.6

Well, glad to be here doing this with you, Peacock. You're like one of those close friends

1:25.3

that I never talk to, never see you. We ain't got no business talking to each other because you're out there and I'm over here, but whatever we do, it's always a good time. I can give you some storylines. For Jacksonville, it's about we. It's about us. It's not even about the opponent, and I know that sounds a little arrogant, but the Jackson of a Jaguar should be 3 and 0.

1:46.0

And the only reason they're not 3 and O is because of the mistakes that they made.

1:48.9

And even in the two games that they won, they made enough mistakes that it could have gone the other way.

1:53.9

And I think when they focus on cleaning up the things that they need to clean up, pre-snap penalties,

2:01.1

they wanted a top two in the league.

2:04.3

Interceptions.

2:05.1

They're one of the top three or four in the league.

...

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