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Science Quickly

Vocal Cords Bioengineered from Starter Cells

Science Quickly

Scientific American

Science

4.2639 Ratings

🗓️ 23 November 2015

⏱️ 3 minutes

🧾️ Download transcript

Summary

Researchers took cells from donated vocal cord tissue and successfully grew them on a three-dimensional scaffold to produce new vocal cords that can produce sound   Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Understanding the human body is a team effort. That's where the Yachtel group comes in.

0:05.8

Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years.

0:11.0

Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program.

0:19.6

To learn more about Yachtolt, visit yawcult.co.j.p.

0:23.9

That's y-A-K-U-L-T dot-C-O-J-P.

0:28.4

When it comes to a guide for your gut, count on YacL.

0:33.5

This is Scientific Americans' 60-second science.

0:37.2

I'm Steve Mersski. Got a minute?

0:40.2

Voice is generated by a complex and beautiful biological system,

0:46.1

and this is a system that allows all of us to communicate messages, concepts, and emotions.

0:52.6

Nathan Wellam of the University of Wisconsin School of Medicine and Public Health.

0:57.0

But a person can lose his or her voice because of severe damage to the vocal cords, also called the vocal fold mucosa.

1:04.0

In these situations where the vocal fold mucosa is severely damaged or missing, and with present technology unfixable, the best

1:13.3

option may be to simply replace it.

1:15.3

Wellam spoke at a telephone press conference on November 17th, in conjunction with the

1:19.9

announcement that he and colleagues had succeeded in generating bioengineered vocal fold

1:24.9

mucosa that were capable of producing sound, a first step toward

1:29.8

implants one day. Their study is in the journal Science. The research team started with vocal

1:35.2

cord tissue from a cadaver and from four patients who had had their voice boxes removed. They took cells

1:40.8

from those tissue samples and successfully grew them on a three-dimensional

1:44.6

scaffold to produce new vocal cords. So how do the lab grown vocal cords actually sound?

1:51.6

We did some functional testing where a larynx is mounted on a lab bench, put on a fake windpipe,

...

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