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Wall Street Breakfast

Viking weight loss pill sees positive early data

Wall Street Breakfast

Seeking Alpha

Business News, News, Business, Investing

4.11K Ratings

🗓️ 4 November 2024

⏱️ 5 minutes

🧾️ Download transcript

Summary

Those with 100mg doses of VK2735 lost an average of 8.2% of body weight. (0:15) Peloton snags a double upgrade. (2:41) Regulators nix Talen-Amazon power deal. (3:47) 

Show Notes
Marriott's full year outlook lowered again on sluggish Chinese markets

Episode transcripts: seekingalpha.com/wsb
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Transcript

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0:00.0

Welcome to Seeking Alpha's Wall Street Lunch, our afternoon update on today's market action, news, and analysis.

0:10.3

Good afternoon. Today is Monday, November 4th, and I'm your host, Kim Kahn. Our top story so far.

0:15.9

Shares of Viking therapeutics are surging after the biotech reported promising results for its experimental obesity

0:21.8

pill with increased weight loss observed at higher doses. Patients on 100 milligram doses of

0:27.6

Vikings VK-2735 lost an average of 8.2% of their body weight after 28 days in an early-stage trial,

0:35.3

or 6.8% more than those taking a placebo. The study includes

0:39.6

92 people taking a variety of dose levels, with 100 milligrams the highest. There are no

0:45.1

discontinuations of the drug at the highest dose, with the most common side effects being

0:48.8

constipation, nausea, and vomiting, similar to other obesity drugs. VK 2735 is a dual GLP-1-GIP receptor agonist,

0:58.8

similar to Eli Lilly's Blockbuster Weight Loss drug Zepbound, designed to treat obesity and other

1:03.7

metabolic disorders. Viking plans to begin a phase two study of the oral VK2735 for obesity before the end of 2024. The oral version is being

1:13.6

developed as an alternative for patients hesitant for injection-based therapy, looking to maintain

1:18.5

their weight loss or transition away from the injectable version of VK2735. According to Dow Jones,

1:25.3

Stiefel analyst Annabel Simimi says,

1:34.9

both oral and injectable VK 2735 continues to boast one of the most competitive profiles in the obesity space,

1:41.2

with strong efficacy and tolerability and now a potential for versatile monthly dosing for maintenance therapy.

1:46.8

In today's trading, stocks are understandably cautious with the election on Tuesday and then a Fed decision on Thursday.

1:48.4

Treasury yields, on the other hand, are significantly lower across the curve, with a tenure

1:52.5

back below 4.3%.

1:54.2

Carol Schleaf, chief investment officer at BMO Family Office, says, any volatility this week

1:59.9

would be a normal pullback in our view,

2:01.9

and an opportunity to put new cash to work, especially cash that has been sitting on the sidelines.

...

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