Over 10 million Americans vape, or smoke electronic cigarettes. E-cigarettes are also the most popular tobacco product among teenagers in this country. Some of them are marketed with bright colors and fun flavors like chocolate, creme brulee, and mint—or they’re advertised as a healthier alternative to regular cigarette smoking. But last week, public health officials reported that a patient in Illinois died from a mysterious lung illness linked to vaping. In 29 states across the country, there are 193 reported cases of this unknown illness as of August 30. Most patients are teenagers or young adults and have symptoms like difficulty breathing, chest pain, vomiting, diarrhea, and fatigue. Patients with more severe cases have to be put on oxygen tanks and ventilators—and some may suffer from permanent lung damage. “Acute lung injury happens in response to all kinds of things, like inhaling a toxic chemical or an infection. This is similar to what we’d see there. The lungs’ protective response gets turned on and doesn’t turn off,” Dr. Frank Leone, a professor of medicine and the director of the Comprehensive Smoking Treatment Program at the University of Pennsylvania, tells Science Friday in a phone call earlier this week. The Centers for Disease Control (CDC) is still investigating the cause, but the illness is raising questions about the health effects of a growing smoking trend and how it should be regulated. “It’s sort of a Wild West out there,” Anna Maria Barry-Jester, a senior correspondent for Kaiser Health News, tells SciFri on the phone about current regulation of electronic cigarettes. Ira talks with Anna Maria Barry-Jester and Dr. Frank Leone about the illness and vaping’s health effects. It’s back to school season for everyone: students, teachers, and Science Friday. Our Educator Collaborative is back with nine teaching resources from nine amazing educators—all inspired by Science Friday media. From a lesson in sauropod digestion, complete with simulated poop (yes, it’s gross), to inventing a way to get plastic out of the oceans, these resources offer learners in the classroom or at home chances to engage directly with complex science and engineering topics. Program member Andrea La Rosa, an eighth-grade science teacher from Danbury Connecticut, joins Ira to talk about a topic near to our hearts: analog and digital technology. She explains how she used a drawing activity to help her students understand how the two kinds of signals are different. Plus, in a world that’s getting increasingly complicated, with more concepts to learn every year, how do you make the most of students’ time in science class? Science Friday education director Ariel Zych talks about the ways educators are teaching young learners to learn, think critically, and take on increasingly high-tech concepts.