Welcome back to the Real Life Pharmacology podcast.

As always, definitely check out Real Life Pharmacology.com.

I've got that free giveaway. It's a great resource.

Top 200 drugs where I highlight three really important things from each of those top 200 medication.

Definitely things you could be tested on throughout your nursing, pharmacy,

med school, whichever health care profession you're in.

If you're taking a pharmacology class, you can definitely be tested on those things.

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So today I'm going to talk about antichcholinergic medications.

Probably more specifically I'm going to talk about some of the urinary anticholinergic medications.

So examples here, oxybutinine, brand name Ditropan, Tolteridine, Detrol, a couple others, Daraphenison,

Nablex, Solophenison, Vesacare.

Now, the mechanism of action and where these medications might be used, these meds block what are called muscarinic receptors,

and specifically in the bladder urinary tract region, it is the M3 receptor.

I've definitely seen that come up on test questions and different things like that.

So they block these muscarinic receptors, and in the bladder and the urinary tract region,

that can cause a contraction which can increase urine volume in the bladder, and it can also

potentially reduce frequency and urge.

So probably the most frequent situation you're going to see these meds used in is urinary frequency

and urge incontinence.

Now, with that said, I mentioned that they do kind of cause

constriction. They kind of help block or reduce the urine flow from coming out. So we do have

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