Ultimate Fat Loss Guide - Gabrielle Lyon - Mike Israetel - Layne Norton - Don Saladino

The Dr. Gabrielle Lyon Show

Dr. Gabrielle Lyon

Medicine, Science, Health & Fitness, Life Sciences

4.6 • 911 Ratings

🗓️ 1 September 2025

⏱️ 109 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this compilation, Dr. Gabrielle Lyon brings together the top minds in health and fitness to deliver the ultimate guide to fat loss. Featuring the best moments with Dr. Mike Israetel, Dr. Layne Norton, and Don Saladino, this video cuts through the confusion and gives you a no-nonsense, science-backed approach to transforming your body.

You’ll hear from the experts on everything from the flawed science of calories to the truth about muscle, metabolism, and modern weight loss drugs like Ozempic. This is not about fads or quick fixes—it’s a masterclass in building a sustainable, healthy body.

Dr. Mike Israetel: The fundamental principles of diet, the reality of "under-eating," and how to manage diet fatigue.

Dr. Layne Norton: The truth about flexible dieting, why calories still count, and the role of protein in weight loss.

Don Saladino: How to optimize your training for fat loss, the importance of consistency, and building a stronger mindset.

This is the only fat loss guide you'll ever need.

Chapters

0:00 - The Protein Debate Begins

1:31 - Debunking the Flawed Science of Protein

15:00 - The Myth of "Wasted" Protein

22:42 - The Truth About the RDA & What "Deficiency" Really Means

50:41 - The Problem with Plant Proteins & Caloric Cost

1:05:22 - The 100-Gram Protein Tipping Point

1:09:10 - Carbs vs. Protein: A Metabolic Showdown

1:13:15 - How to Diagnose a Protein Deficiency

1:18:13 - Final Thoughts: The Path Forward

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Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Transcript

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0:00.0	For every 10 people who lose weight, only one will keep it off for good.
0:04.5	How you would think about fat loss.
0:07.2	Because that's what everybody wants.
0:08.5	You don't have to count your calories, but it's really good idea to understand that calories matter.
0:13.8	Most people don't fail because they're lazy or lack willpower.
0:17.8	They fail because they're following the wrong strategy. So what's the right
0:22.3	strategy? Listen, we need strength training three days a week at a bare minimum. The number one most
0:26.6	important thing, get your energy intake correct. If you want to lose fat, you have to consume less
0:32.4	energy than you expend. Dieting is tough. A condition in which your body is not getting sufficient
0:36.8	calories to maintain his weight almost always accrues some fatigue. And we call that diet fatigue in the industry.
0:42.7	By mastering these strategies or habits, you can lose weight and keep it off. No gimmicks. No fat diets.
0:49.0	Just science-backed proven methods. So we took care of most of the theory behind how people can lose weight.
0:55.7	But there's a missing piece.
1:00.7	The world is really confused about fat loss, about muscle.
1:09.3	Where can we start with fat loss?
1:11.7	People that are loudly proclaiming things that are one of two categories, wild
1:17.1	exaggerations or things that are just categorically untrue.
1:20.5	And give me an example.
1:21.5	Yes, yes.
1:23.2	Categorically untrue.
1:24.8	Calorie balance is a myth.
1:26.6	Calories don't matter. Wild exaggeration.
	...

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