TWiV 916: COVID-19 clinical update #122 with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 9 July 2022

⏱️ 47 minutes

🔗️ Recording | iTunes | RSS

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Summary

In COVID-19 clinical update #122, Dr. Griffin discusses vaccine availability and coverage among children, post-infection health impairments in children and adolescents, infection detection using salvia and nasopharyngeal samples, effectiveness of vaccines during delta dominance, durability of vaccine against severe outcomes, concern in the postvaccination era, infection rebound after Paxlovid & Molnupiravir, lack of improvement after adding ivermectin to standard care, duration of shedding of virus, how thromboprophylaxis reduces thromboembolism but increases major bleeding, multi-lineage neural and myelin dysregulation caused by infection, and the association between vaccination and post-acute infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode The next epidemic may be here (STAT) Vaccine availability and coverage among children (CDC) Post-infection health impairments in children & adolescents (Pediatrics) Infection detection using saliva & nasopharyngeal samples (Journal of Medical Virology) Effectiveness of vaccines during Delta dominance (The Lancet) Durability of vaccine against severe outcomes (The Lancet) Don’t rush to change COVID vaccines (STAT) Concern in the postvaccination era (Immunity, Inflammation and Disease) Infection rebound after Paxlovid & Molnupiravir (medRxiv) No improvement after Ivermectin usage (ACP) Duration of shedding of virus (New England Journal of Medicine) Infectious viral load vaccinated vs unvaccinated (Nat Med) Thromboprophylaxis reduces thromboembolism (NIH) Multi-lineage neural cell and myelin dysregulation caused by infection (Cell) Association between vaccination and post-acute infection (JAMA) Contribute to FIMRC fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 916 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From micro-optv, this is TWIV, this week in virology, Episode 916 recorded on July 6th, 2022.
0:20.9	I'm Vincent Racken-Ello, and you're listening to the podcast all about viruses,
0:25.7	joining me today from New York, Daniel Griffin.
0:30.2	Hello everyone.
0:31.5	Actually, you're not joining me from New York.
0:33.5	This is true. Joining you from a small island off the Atlantic coast of Spain.
0:38.7	Very nice.
0:39.5	So if you hear the sound of ocean in the background or the wind, that's what it is.
0:44.5	But let me jump in, and we always have a lot, but let me start with my quotation.
0:49.8	And this is from Ray Bradbury, Fahrenheit 451.
0:54.2	But you can't make people listen.
0:56.6	They have to come round in their own time, wondering what happened and why the world blew up around them.
1:02.8	So I'm a busy reading Fahrenheit 451.
1:05.9	So I will maybe have some quotations from it in the future.
1:10.1	But I'm going to jump in, and actually this is going to be this question.
1:15.5	Did we learn during this pandemic?
1:18.6	Did we make changes based on the lessons learned that improve how we will respond to the next infectious disease challenge?
1:25.8	I think you may have actually picked this as one of your twiff fix, Vincent.
1:30.0	That's correct. I did, yes.
1:31.8	So I was listening to the twiff episode, and lo and behold,
1:37.7	this opinion piece that was in stat, the next epidemic, maybe here, the US isn't ready for it.
	...

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