TWiV 1301: Lost in giant virus translation

This Week in Virology

Vincent Racaniello

Virology, Science & Medicine, Pathogen, Infection, Virus, Racaniello, Twiv, Vincent, Microbe, Medicine, Infectious, Microbiology

4.8 • 2.2K Ratings

🗓️ 1 March 2026

⏱️ 125 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral structural proteins. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) LCMV seroprevalence among pregnant women (Emerg Inf Dis) Giant viruses encode functional vIF4F (Cell) Ribosomal proteins encoded in viral genomes (virology blog) Letters read on TWiV 1301 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – “The Song of the Cell” by Siddhartha Mukherjee. Kathy – Fitbit for farts (WSJ and 1° article) Rich – The Password That Lets Caterpillars Hide in an Ant’s Lair Vincent – Astrophysics for People in a Hurry by Neil deGrasse Tyson Listener Pick Larry – Get an early start! (primary article) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This Week in Virology, the podcast about viruses, the kind that make you sick.
0:10.6	From MicrobTV, this is Twiv, this week in Virology.
0:15.7	Episode 1301 recorded on February 27th,26. I'm Vincent Rackeniello, and you're listening to the podcast
0:27.6	All About Viruses. Joining me today from Montreal, Canada, Angela Mingarelli.
0:36.4	Hello, how's everyone today?
0:38.8	You get warmer?
0:39.9	Is it warmed up a bit or it's still freezing up there?
0:42.4	Well, so it's still freezing.
0:43.5	It's still below zero, at least Celsius.
0:46.3	But within the last two weeks, it's gotten a lot warmer.
0:49.5	So it was like minus 15, minus 20 for over a month.
0:53.7	Yesterday it was minus 14. What's that in Fahrenheit? Because if not, people are going to kill me. No, I like Fahrenheit. Minus 14, I don't know. That's like, I don't, what would that be? Around zero? Is that less than zero? I don't know. Yeah, well, well, minus 4. Zero Celsius is 32 is 32 Fahrenheit. So it's not going to be less
1:14.4	than zero Fahrenheit. This is going to be like five, I guess, something like that. And yesterday,
1:18.6	I didn't even wear a scarf. Minus 14 felt warm. I wasn't even wearing a scarf. I had my coat open
1:23.1	and I was like, this is nice. But today, it's only minus three right now.
1:27.5	So that's like 27, 28 something, which is warm.
1:32.6	Warm.
1:33.2	Also joining us from Ann Arbor, Michigan, Kathy Spindler.
1:37.0	Hi, everybody.
1:37.8	Here it's 54 Fahrenheit, sunny, and that's 12 degrees Celsius.
1:44.7	So nice. Pretty mild there. Is there any snow left on the ground? sunny, and that's 12 degrees Celsius. So it's quite a bit warmer.
1:46.3	Is there any snow left on the ground?
	...

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