TWiV 1217: Alternative vax and pandemic origins

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 11 May 2025

⏱️ 113 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

TWiV reviews new CBER chief at FDA, ending of Gates Foundation in 2045, gain of function executive order, origins of bat viruses ancestral to SARS-CoV and SARS-CoV-2, and single dose Sudan virus replicon vaccine protects guinea pigs from disease. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Prasad replaces Marks at FDA (US News) Gates Foundation ends 2025 (Gates Foundation) Gain of function Executive Order (White House) DURC policy (HHS) Origins of bat viruses ancestral to SARS-CoV and SARS-CoV-2 (Cell) Sudan virus replicon vaccine (Nat Comm) Letters read on TWiV 1217 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Rich – Andor Season 2 Alan – Sequencing Mendel’s pea plant traits, and a good Science news article on the work Vincent – 2023 summer warmth unparalleled over the past 2,000 years Listener Pick Brian – Virology Capabilities Test (VCT): A Multimodal Virology Q&A Benchmark Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This Week in Virology, the podcast about viruses, the kind that make you sick.
0:10.4	From MicrowTV, this is Twiv, this week in Virology, episode 1217, recorded on the 9th of May 2025.
0:23.2	I'm Vincent Rackeniello, and you're listening to the podcast All About Viruses.
0:28.8	Joining me today from Western Massachusetts, Alan Dove.
0:33.3	Good to be here.
0:34.8	And it's been a pluvios week.
0:38.4	And we're continuing that trend today.
0:40.9	Yes.
0:42.2	It is pouring rain, little misty and foggy, 55 Fahrenheit 13C.
0:49.6	Supposed to continue like this through halfway through tomorrow and then clear up and be lovely on Sunday.
0:56.4	Pluvios. I'd already forgotten that one.
0:58.0	I didn't use it. I looked it up, but I forget what it means.
1:02.3	Rainy.
1:03.3	Rainy. Rainy.
1:05.0	No kidding.
1:06.0	All week. Pluvios here all week.
1:08.4	Yeah. Wow. Okay.
1:10.4	Also joining us from Austin, Texas, Rich Condit.
1:13.2	Oh, yeah, I jumped a gun, didn't I?
1:14.5	Yeah, I've been introduced.
1:15.4	It doesn't matter.
1:16.2	It's all right.
	...

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