TWiV 1203: What's old is flu again

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 23 March 2025

⏱️ 117 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV explains why RFK Jr.’s proposal to let H5N1 infections in birds ‘rip’ is a bad idea, phase 1/2 trial of combined influenza/COVID mRNA vaccines, and how your first influenza virus exposure shapes the B cell response to influenza vaccination 50 years later. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 RFK Jr. says let H5N1 rip through flocks (NY Times) Combined flu/COVID mRNA vaccine (Nat Comm) Rare syndrome after COVID vaccination (NY Times, medRxiv) Imprinting lasts 50 years (Immunity) Imprinting protects against H5N1 and H7N9 (Science) Letters read on TWiV 1203 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Node-Focal Plane Image Competition Rich – Periodic cooking of eggs Vincent – The use of placebo controls in clinical trials Listener Picks Anne – Everything is Tuberculosis by John Green Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This Week in Virology, the podcast about viruses, the kind that make you sick.
0:10.3	From MicrowTV, this is Twiv. This Week in Virology, episode 1203 recorded on March 21st, 2025.
0:23.4	I'm Vincent Rackenello, and you're listening to the podcast, All About Viruses.
0:28.8	Joining me today from Madison, New Jersey, Brianne Barker.
0:32.1	Hi, it's great to be here.
0:34.5	It is 49 Fahrenheit, 9 Celsius here.
0:39.1	And I'm looking forward to talking about viruses.
0:43.3	Yeah, we are going to talk about influenza viruses and influenza vaccines today.
0:50.0	Both papers, same top, similar topic.
0:53.8	Here in New York, it is 10 Celsius and sunny-ish.
0:59.4	And I have to look at my phone to find this out because it's a little windy, I think, here.
1:04.2	And I'm excited about potentially not having influenza since I've had respiratory infection
1:10.6	recently and it's unpleasant.
1:12.8	So yay for things that involve us being able to combat influenza.
1:17.9	Vaccines do it.
1:19.1	Vaccines are the best solution for preventing viral disease.
1:23.7	And if you think otherwise, you're just wrong.
1:26.6	Do you like being wrong?
1:28.8	Also joining us from Austin, Texas, Rich Condit.
1:31.7	I think some people do like being wrong. Really?
1:34.4	Yeah, sure, because it gives you something to, you know, be sort of
1:39.0	about, okay? All right. Hi, everybody.
	...

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