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This Week in Virology

TWiV 1140: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.82.2K Ratings

🗓️ 17 August 2024

⏱️ 55 minutes

🧾️ Download transcript

Summary

In his weekly clinical update, Dr. Griffin discusses the harms of perpetuating the lab leak hypothesis and the recent ACIP recommendations for the RSV vaccine for those individuals over 60, before reviewing the recent statistics on SARS-CoV-2 infection, treatment guidelines for the different phases of COVID, including vaccines, Pemgarda, early treatment with Paxlovid, remdesivir and molnupiravir, steroids at the right time, anticoagulation support, immune modulation in some cases, and a comprehensive definition of long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Measles transmission after secondary vaccination failure (Emerg Inf Dis) Mpox public health emergency of international concern (WHO) First case of new mpox strain outside of Africa (Reuters) COVID-19 national trend (CDC) COVID-19 deaths (CDC) Where to get pemgarda (Pemgarda CDC Quarantine guidelines (CDC) Early phase of SARs-CoV-2 infection (COVID.gov) Individual monoclonal antibodies against SARS-CoV-2 should be used (CID) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID science, research and policy (Nature Medicine) Measurements of prior SARS-CoV-2 infection and postacute sequelae by the clinical laboratory (Annals of Internal Medicine) Risk factors for long COVID syndrome in postmenopausal women with previous SARS-CoV-2 infections (Annals of Epidemiology) New studies estimate long-COVID rates, identify risk factors (CIDRAP) Monitoring long COVID via telemedicine (PLoS One) Letters read on TWiV 1140 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0

This Week in Virology, the podcast about viruses, the kind that make you sick.

0:07.0

From Microbe TV, this is Twive, this weekend virology, episode 1140, recorded on Thursday, August 15, 2024. I'm Vincent Drackin-yellow and you're listening to the

0:26.0

podcast all about viruses. Joining me today from New York, Daniel Griffin.

0:32.2

Hello everyone. It ties really... New York, Daniel Griffin.

0:32.8

Hello everyone.

0:34.4

It ties really dark, but I'm gonna guess

0:37.7

it's a Diplococcus.

0:40.0

So close, they are these little cox-eye. They're actually they're in clusters and they are a golden color. So think of the

0:50.0

golden grape. So can you say grape in Greek? Oh yes of course I know what that is is that

0:58.2

streptococcus? Staff leococcus. Orius. Yeah, staphylococcus orius. I mean they used to be Staff Lachococococococococococous.

1:03.7

I mean they used to be something was called Diplococcus because they were pairs, right?

1:07.8

Yeah, so that's strep Numa, Diplocsi.

1:10.5

You don't use Diplococcus anymore, right?

1:13.0

You know, some of us are old enough to remember that terminology and bantered about, but yes.

1:18.0

Because when I went to graduate school, that's what we called it.

1:23.0

Diplacoxi.

1:24.0

Yeah, that works.

1:25.0

Okay.

1:27.0

All right, well let's jump in.

1:29.0

We'll start with our quotation because we have a bunch to talk about tonight.

1:32.0

And this is from Thomas Carlyle. He who has

1:36.8

health has hope and he who has hope has everything. And just really you, sort of putting up there the importance of health and why we prioritize it.

...

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