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This Week in Virology

TWiV 1100: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.82.2K Ratings

🗓️ 30 March 2024

⏱️ 44 minutes

🧾️ Download transcript

Summary

In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles influenza and SARS-CoV-2, before discussing the development of new monoclonal antibody therapy, if vaccines and antivial drugs can used effectively together. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound including that after administration of the “oral remdesivir”, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if one can predict the loss infectivity of healthcare workers with mild COVID-19 disease and the dynamics of household transmission of the virus in children. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Measles tracking (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) What new monoclonal antibody therapy? (FDA) A New pre-exposure prophylaxis for COVID-19? (Invivyd) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Really COVID-19 rebound after Nirmatrelvir-ritonavir treatment? (JAMA Network Open) Can vaccines and antiviral be effective for COVID-19 together (International Journal of Infectious Diseases) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Can loss of infectivity among healthcare works with mild and recurrent COVID-19 be predicted (CID) Household transmission dynamics in children with asymptomatic infection (CID) Steroids,dexamethasone at the right time (OFID)Anticoagulation guidelines (hematology.org) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1098 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0

This Week in Virology, the podcast about viruses, the kind that make you sick.

0:07.0

From Microbe TV, this is Twive, this weekend virology, episode 1100,

0:18.8

1,100, to figure out how to do that. Recorded on March 28, 2024. I'm Vincent Rachin-yellow

0:28.1

and you're listening to the podcast all about viruses. Joining me today from New York, Daniel Griffin.

0:35.4

Hello everyone.

0:37.1

So should it be 1100 or 1,100 Daniel?

0:40.5

Oh, you know, I think both are okay. I don't know if there's any, you know, any,

0:47.0

anyone that has precedence over the other.

0:50.0

So, you know, when you say 1958, it's 90 90 it's not 1,958 so it should be

0:56.8

1100 yeah yeah I mean I think it'll be interesting as next time it'll be like

1:02.4

1102 like I'll say that

1:04.4

like 1102 is a lot easier to say than 1,102 right just gets to be a little

1:09.1

well when when we were in 2000 though we said 2000 yeah not 20

1:13.7

2002 20 author or something you know actually that's yeah I guess we used to say like

1:19.8

I remember my kids were born like 2000, 2002, 2005, but now I say like you know I would say like

1:26.2

oh someone so was born in 2024.

1:29.2

Yeah that's much easier once you get into the tens right 2010 so when we get to 2,000 I think I know what

1:35.4

we'll do but yeah so what's on your bow tie today Daniel you know this is very hard to see so I don't know if anyone's going to zoom in on it, but it's supposed to be strep numo.

1:49.0

So, you know, if anyone zooms in,'s these little gram positive cocksi they're not

1:56.2

really in pairs the way I would like so you know sometimes they're

1:59.7

they used to call it Diplacakis right yeah yeah yeah and then they said well they're not all these

2:05.6

pairs so we better change yeah sometimes they're in strips okay good all right so let's jump right into it. Our knowledge can only be finite,

...

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