TWiV 1025: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 15 July 2023

⏱️ 35 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses the new risk assessment for the H5N1 avian flu viruses, the development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure in animals, repeated antibiotic exposure and risk of hospitalization and death following COVID-19 infection, COVID-19 rebound study: a prospective cohort study to evaluate viral and symptom rebound differences in participants treated with Nirmatrelvir plus Ritonavir versus untreated controls, exaggerated blood pressure elevation in response to orthostatic challenge a post-acute sequelae of SARS-CoV-2 infection (PASC) after hospitalization, long term follow-up of a multicenter cohort of COVID-19 patients with pulmonary embolism, and risk of cardiovascular disease after COVID‐19 diagnosis among adults with and without diabetes. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode New risk assessment for H5N1 avian flu viruses (CDC) Development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure (Virology) Repeated antibiotic exposure and risk of hospitalization and death following COVID-19 infection (eClinicalMedicine) COVID-19 Rebound Study (CID) Exaggerated blood pressure elevation in response to orthostatic challenge (AN) Long term follow-up of a multicenter cohort of COVID-19 patients with pulmonary embolism (TR) Risk of Cardiovascular disease after COVID‐19 diagnosis among adults with and without Diabetes (JAHA) Contribute to our FIMRC fundraiser at PWB Letters read on TWiV 1025 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.3	From micro TV, this is TWIV, this week in virology, episode 1025 recorded on July 12,
0:21.0	2023. I'm Vincent Racken, yellow, and you're listening to the podcast all about viruses
0:28.6	joining me today from New York, Daniel Griffin. Hello, everyone. This is not something that anyone
0:36.2	cares about, but ever since TWIV 1000, the clinical updates have gotten an even number.
0:42.0	If you do two a week, one is going to be even and one is going to be odd. But this week, I stuck
0:50.8	in an extra midweek episode with Coist yet to mchoff, really good interview. You have to listen.
0:57.1	And now Daniel, you're going to be stuck on odd numbers for a while. So from here on out, all my
1:03.0	updates will be odd. That's right. So let's have an odd update, Daniel. Okay. So I'll start with my
1:12.2	quotation. Now, unfortunately, people who are followers may have heard that Milan Kondera, the author
1:18.6	of the unbearable lightness of being past this week. So I actually changed just this morning to
1:24.6	a different quotation and let me go ahead with it. For there is nothing heavier than compassion,
1:31.2	not even one's own pain weighs so heavy as the pain one feels with someone for someone,
1:38.6	a pain intensified by the imagination and prolonged by 100 echoes. Huge phantom Milan Kondera. So
1:46.6	that, you know, those of you that haven't had a chance to read any of the works, I highly recommend
1:52.9	them. I remember one time I was talking to, I think it was the head of the Nobel Prize Committee.
1:58.0	And his, his advice was to read broadly, not just stick in your little area, but try to sort of
2:06.2	bring some breath to things. And with that, I will talk about flu. So the, the CDC recently
2:14.7	published a new risk assessment for the H5N1 avian flu viruses that continue to circulate in wild
2:21.6	birds and poultry, also impacting some cats. People are following that. For background, the
2:27.7	influenza risk assessment tool, the irat is an evaluation tool conceived by CDC further
2:34.6	developed with assistance from global animal and human health influenza experts. And the irats
	...

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