TWiV 1007: Fragile DNA, viruses, cancer

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 14 May 2023

⏱️ 101 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV explains genetic changes in nOPV2 strains that paralyzed children, outbreak of raccoon distemper in Toronto, EcoHealth Alliance gets its NIH grant back, and breakage at chromosomal fragile sites caused by the EBNA1 protein of Epstein-Barr virus as a mechanism for carcinogenesis. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Register for ASV 2023 Research assistant position at FDA (pdf) MicrobeTV Discord Server nOPV2 after two years (Polioeradication) Raccoon distemper in Toronto (CityNews Everywhere) NIH reinstates EcoHealth grant (Nature) Chromosomal breakage by EBNA1 (Nature) Agent of chromosomal instability (Nature) Timestamps by Jolene. Thanks! Weekly Picks Angela – Night Science Kathy – Kermit, Jim Henson, Rainbow Connection Rich – Alexander Skarsgård Explains the Answer to Everything Vincent – Beyond the Noise with Dr. Paul Offit Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.3	From micro TV, this is Twiv, this week in virology episode 107 recorded on May 12, 2023.
0:21.4	I'm Vincent Rackenello, and you're listening to the podcast all about viruses joining me today
0:27.8	from Ann Arbor, Michigan, Kathy Spindler. Hi everybody. Here one of my apps says that it's 80
0:34.6	Fahrenheit, and the Norwegian weather app says that it's 23 Celsius, and both of them say that
0:40.8	it's cloudy throughout the day. It might rain a little bit later, but it's a pretty good day,
0:44.6	pretty warm. Yeah, we have 30 Celsius here. It's like 86. It's really warm today, but I'm inside
0:53.5	the air conditioning is kicking in now, which I don't need, and it's noisy, which I don't like.
0:58.8	I can't control it. Oh well, also joining us from Austin, Texas, Rich Condit.
1:04.8	Hi everybody. 83 degrees overcast. Rain in the future, according to the weatherman, and they seem
1:14.8	really pretty convinced of this, this time we could, and you know, we're like 30%,
1:20.7	15 to 30% behind in our annual rainfall, depending on whose counting.
1:26.3	We could use this, and this may go a long way to making it up. We're looking at maybe a couple
1:30.4	of inches over the next couple of days, which would be great. And from Montreal, Canada, Angela
1:36.8	Mingurally. Hello everyone. So it is 75 degrees Fahrenheit here. I checked, which is 24 Celsius,
1:45.3	and it's actually surprisingly warm. We're very excited in Montreal, because the temperature has not
1:52.9	gone below five degrees in about a week, and the weather next week, the weather prediction looks good.
1:59.3	It looks like we're going to stay around the teens during the day, so summer is finally coming.
2:04.2	We're excited. Cool. Isn't it supposed to be spring first? Well, true, but we kind of skip,
2:10.2	we don't really have a lot of spring in Montreal. We go from like zero to 25 in three days. So
2:16.4	I remember when I lived in Buffalo, somebody gets a visitor getting off a plane sometime in early
2:22.2	May, and kind of looking around and telling me, you know, it's spring everywhere else.
	...

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