Turning anemones into coral, and the future of psychiatric drugs

Science Magazine Podcast

Science Podcast

News Commentary, News, Science

4.2 • 791 Ratings

🗓️ 2 November 2023

⏱️ 39 minutes

🔗️ Recording | iTunes | RSS

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Summary

Why scientists are trying to make anemones act like corals, and why it’s so hard to make pharmaceuticals for brain diseases First up on this week’s show, coaxing anemones to make rocks. Newsletter Editor Christie Wilcox joins host Sarah Crespi to discuss the difficulties of raising coral in the lab and a research group that’s instead trying to pin down the process of biomineralization by inserting coral genes into easy-to-maintain anemones. Next on the show, a look at why therapeutics for both neurodegenerative disease and psychiatric illness are lagging behind other kinds of medicines. Steve Hyman, director of the Stanley Center for Psychiatric Research at the Broad Institute, talks with Sarah about some of the stumbling blocks to developing drugs for the brain—including a lack of diverse genome sequences—and what researchers are doing to get things back on track. Finally, in a sponsored segment from the Science/AAAS Custom Publishing Office, associate editor Jackie Oberst discusses with Thomas Fuchs, dean of artificial intelligence (AI) and human health and professor of computational pathology and computer science at the Icahn School of Medicine at Mount Sinai, the potential and evolving role of AI in health care. This segment is sponsored by the Icahn School of Medicine at Mount Sinai. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Christie Wilcox; Sarah Crespi Episode page: https://www.science.org/doi/10.1126/science.adm6756 Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:30.8	Choose the solution that is tested, validated, and approved by leading instrument manufacturers globally. Visit PeekScientific.com and quote Science Podcast to receive special offers.
0:37.1	This podcast is supported by the Icon School of Medicine at Mount Sinai,
0:41.3	one of America's leading research medical schools.
0:44.7	Icon Mount Sinai is the academic arm of the eight hospital Mount Sinai health system in New York
0:50.0	City.
0:50.8	It's consistently among the top recipients of NIH funding. Researchers at ICONMount
0:56.3	Sinai have made breakthrough discoveries in many fields vital to advancing the health of patients,
1:02.0	including cancer, COVID, and long COVID, cardiology, neuroscience, and artificial intelligence.
1:09.2	The Icon School of Medicine at Mount Sinai, we find a way.
1:16.6	This is the science podcast for November 3rd, 2023.
1:22.6	I'm Sarah Crespi.
1:24.6	First up on this week's show, turning anemones into corals. Newsletter editor,
1:30.2	Christine Wilcox, joins me to discuss why anyone would want to do this and a few other fun animal
1:35.6	stories from the site, like measuring primate menopause and counting cat facial expressions.
1:41.5	Next up on the show, why it's so hard to make drugs for brain diseases?
1:46.1	Researcher Stephen Hyman talks about the state of treatments for neurological and psychiatric disorders
1:51.5	and how to overcome some of the big hurdles in the field. Finally, in a sponsored segment from
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