Toxicology
EM Clerkship
Zack Olson, MD ; Mike Estephan, MD ; Maddie Watts, MD
4.9 • 816 Ratings
🗓️ 4 July 2016
⏱️ 9 minutes
🧾️ Download transcript
Summary
Poison Control Hotline: 1-800-222-1222
Step 1: Evaluate the Airway
* General principles* “If they can’t speak, they can’t control their airway”* “If GCS is <8, intubate”* In the real world, it’s a clinical judgement call
Step 2: Toxicology History
* What did they take? * How much did they take?* Why did they take it?* When did they take it?
Step 3: Toxicology Exam
* Vital signs* Pupils* Skin
Step 4: Medication List
* Make note of all bottles with patient* Make EXTRA note if any pills seem to be missing* Bonus points if you bring your attending a med list
Step 5: Common Toxicology Tests
* Assessing for damage* Electrolytes* Liver function test* EKG* Pregnancy* Assessing for co-ingestion* Serum acetaminophen* Serum salicylate* Serum alcohol* Urine drug screen
The “Big 5” Toxidromes
* Anticholinergic* Increased vitals* Big pupils* Dry skin* Treatment – Physostigmine (rarely given)* Cholinergic* Decreased vitals* Small pupils* Moist skin* Treatment – Atropine* Opioid* Decreased vitals* Small pupils* Dry skin* Treatment – Naloxone* Sedative/Hypnotic* Decreased vitals* Normal pupils* Dry skin* Treatment – Flumazenil (rarely given)* Sympathomimetics* Increased vitals* Big pupils* Moist skin* Treatment – Benzodiazepines
Additional Reading
* NBME Shelf Review – Ophthalmology and Toxicology (EM Clerkship)* Toxidromes (Admin EM)
Transcript
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| 0:00.0 | Hello, med students. This episode has been sponsored by Freed AI. Do you dread the thought of |
| 0:07.1 | endless charting once you become a doctor? Do you think that doctors should be spending more |
| 0:11.9 | time with our patients and less time mindlessly writing notes? Freed AI is the product for you. It is a |
| 0:20.4 | secure, hippocompliant scribe that anybody can use. |
| 0:24.7 | Focus your energy on what matters, providing good patient care. |
| 0:29.5 | Use coupon code EM50 to save 50% the first month you try it, |
| 0:34.1 | and you can cancel at any time if you decide it's not right for you. You can learn more |
| 0:38.9 | at www.gitfreed.a.i. Hello, med students. My name is Zach Olson. Thank you for downloading this |
| 0:49.9 | episode of the EM Clerkship Podcast. I want you to close your eyes and imagine. In front of you |
| 0:56.6 | is a 40-year-old female. She's being wheeled in by EMS with severe altered mental status. |
| 1:04.0 | Her blood sugar is normal, but they do report that the patient had several empty pill bottles nearby. |
| 1:10.4 | Pause here. |
| 1:11.6 | What is your next step? |
| 1:18.5 | Today, we're going to cover toxicology. |
| 1:22.6 | This episode's actually going to be broken down into two parts. |
| 1:26.3 | The first part is the quick approach to any toxicology case. |
| 1:30.6 | And then in part two, I'm going to go through the big five toxodromes as laid out in Tintanallies. |
| 1:36.8 | So this is going to be a pretty intense episode. |
| 1:38.9 | I need you guys to hang with me today. |
| 1:40.9 | The thing that I'm going to want you to remember from this episode is that you have to look |
| 1:45.7 | at the patient's vitals, pupils, and skin. Vital's pupils skin. We're going to go into that more |
| 1:51.6 | in a bit, but let's just start out with our basic approach. Step one, airway. Just like with trauma, |
... |
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