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The Dr. Josh Axe Show

This Is What Happens to Your Brain When You Heal Your Gut

The Dr. Josh Axe Show

Dr. Josh Axe

Christianity, Religion & Spirituality, Health & Fitness

4.91.4K Ratings

🗓️ 1 September 2025

⏱️ 42 minutes

🧾️ Download transcript

Summary

Ever wonder why anxiety, brain fog, or even memory loss often come hand-in-hand with digestive issues? In this episode, Dr. Josh Axe unpacks the fascinating science of the gut-brain connection, showing how your microbiome and vagus nerve directly shape your mood, focus, and long-term brain health. You’ll also discover the hidden gut disruptors sabotaging your mental clarity—and the foods, herbs, and daily habits that can restore balance, sharpen your mind, and protect against everything from depression to Alzheimer’s. Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1  🎧 Early Access! Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners →  Spotify: https://bit.ly/DrJoshAxeSpotify Apple Podcast: https://apple.co/3JDvWcS Pre-order my NEW BOOK, The Biblio Diet → https://bit.ly/4oPEP3t Check out Wheat Belly by Dr. William Davis → https://www.amazon.com/Wheat-Belly-Lose-Weight-Health/dp/1609614798  Read Grain Brain By Dr. David Perlmutter → https://www.amazon.com/Grain-Brain-Surprising-Sugar-Your-Killers/dp/031623480X  Order my book, Eat Dirt → https://www.amazon.com/Eat-Dirt-Health-Problems-Surprising/dp/0062433644  Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! →  MyBloodWork.com  CONNECT WITH DR. JOSH AXE Instagram→ https://www.instagram.com/drjoshaxe/ Facebook → https://www.facebook.com/DrJoshAxe/ TikTok → https://www.tiktok.com/@thedrjoshaxeshow/ X → https://x.com/drjoshaxe/ LinkedIn → https://www.linkedin.com/in/joshaxe Website →  http://thehealthinstitute.com Sign up for my newsletter → https://bit.ly/4oE9Jf3 Ask Dr. Axe → http://speakpipe.com/drjoshaxe   Links:  https://my.clevelandclinic.org/health/articles/22572-serotonin https://www.webmd.com/ibs/stress-anxiety-ibs https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2020.572912/full https://pubs.rsc.org/en/content/articlelanding/2024/fo/d4fo00660g/unauth https://pmc.ncbi.nlm.nih.gov/articles/PMC12025785/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5591346/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7651765/ https://pmc.ncbi.nlm.nih.gov/articles/PMC10316519/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6678997/ https://pmc.ncbi.nlm.nih.gov/articles/PMC10893170/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5641835/ https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.00421/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8609682/ https://news.harvard.edu/gazette/story/2024/12/does-parkinsons-start-in-the-gut-brain-microbiome/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5766597/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7285525/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6471505/ https://pmc.ncbi.nlm.nih.gov/articles/PMC9881072/ https://medicine.yale.edu/news-article/gut-microbiome-changes-linked-to-multiple-sclerosis-ms-new-study-finds/ https://pmc.ncbi.nlm.nih.gov/articles/PMC9881072/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7703666/ https://www.nature.com/articles/s41392-024-01743-1 Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

If you have a health issue, one of the number one things you're probably overlooking is your gut brain connection.

0:06.9

You have a connection between your mind and your body and most people overlook this and don't care for it the right way.

0:13.2

And because of it, they're suffering with health issues.

0:16.0

For instance, brain fog, poor memory, not being able to focus or concentrate or lack of motivation,

0:23.1

oftentimes doesn't start in the brain, it starts in the gut, or issues like IBS, gas,

0:30.5

bloating, any type of digestive issue, oftentimes that starts in the brain. In this episode,

0:35.7

I'm going to dive into the practical things I've done in my clinic and the

0:39.6

science behind how to heal your gut brain connection, including the ideal diet, herbs, lifestyle

0:46.2

medicine, and other practices to heal your gut brain connection.

0:49.9

Welcome to the Dr. Joshak Show.

1:08.2

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1:09.4

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1:14.7

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1:17.3

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1:19.1

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1:23.3

So before I dive into the top seven things that are disrupting your gut, let's talk about what the gut brain connection actually is.

1:31.8

The gut brain axis is the bidirectional communication network between your gut and your brain.

1:38.7

In fact, also it's important to know that your gut is often called your second brain because it has the second most neurological

1:46.0

tissue to your brain and it communicates with numerous really every organ and cell and tissue

1:52.3

in your body and the gut brain axis involves your neural and your hormonal and your immune

1:59.0

signals that keep your body balanced or throw it off.

2:02.6

So the gut brain axis includes, one, this is really important,

...

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