The Science of How Mitochondria Regulate Skin Longevity - Timeline Masterclass Part 2
Skin Anarchy
Ekta et al.
4.2 • 2K Ratings
🗓️ 13 October 2025
⏱️ 37 minutes
🧾️ Download transcript
Summary
In this masterclass episode of Skin Anarchy, Dr. Ekta Yadav sits down with Dr. Julie Faitg, Senior Manager of Applied Research and Regulatory Affairs at Timeline, to uncover how mitochondrial science is transforming the future of skin longevity.
Dr. Feitge challenges the familiar “powerhouse” analogy, instead calling mitochondria the “CEO of the cell.” Far from passive energy producers, these organelles orchestrate communication, repair, and renewal—directly influencing collagen production, elasticity, and cellular resilience. “If your mitochondria aren’t healthy,” she explains, “the entire cascade of cellular function begins to falter.”
Through vivid analogies, Dr. Feitge describes how mitochondria behave differently across tissues—fueling endurance in muscles, focus in the brain, and regeneration in the skin. This adaptability, she notes, is what makes them the foundation of both vitality and longevity.
The conversation dives into mitochondrial resilience, the skin’s ability to repair and recover from stress. Aging begins when this resilience declines, leading to diminished energy, slower renewal, and visible signs of fatigue.
Dr. Faitgd highlights Timeline’s breakthrough ingredient, Mitopure® (Urolithin A)—a clinically validated compound that triggers mitophagy, the process of recycling damaged mitochondria. In trials, topical Mitopure® improved collagen expression, hydration, and firmness while reducing inflammation and UV-induced stress.
Developed in Switzerland under rigorous safety and precision standards, Timeline’s skincare line redefines beauty as m—a shift from treating the surface to revitalizing the source.
🎧 Listen to this episode to explore how mitochondrial health holds the key to radiant, resilient, and truly ageless skin.
Learn more about Timeline and shop their products on their website and social media.
Chapters:
0:02 – Episode Introduction & Guest Welcome
1:01 – Why Mitochondria Matter & Overview
3:34 – Mitochondria Across Different Tissues
5:22 – Mitochondria’s Role in Skin Vitality
7:04 – Dysfunction, Aging & Skin Longevity
12:19 – Mitochondrial Resilience & Oxidative Stress
18:48 – Clinical Studies & Observed Effects on Skin
21:32 – Delivery Systems, Penetration, & Safety Considerations
25:40 – Translating Swiss Science from Lab to Product
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Transcript
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| 0:00.0 | Hey guys, welcome back to Skin Anarchy. This is episode two in the master class with Timeline. |
| 0:06.2 | I am so excited to be introducing you guys to a researcher and a scientist who knows so much about mitochondrial health, mitochondrial physiology. |
| 0:15.4 | She's really spearheading the work the timeline is doing on that level. So without further ado, please welcome Dr. Julie Feidke, senior manager, applied research and regulatory affairs at Timeline. Welcome, Dr. Julie. Thank you very much for having me in this podcast, really. Thank you. Oh, I'm so excited to talk to you. You know, I was, as we were talking about earlier before the show, I mean, I'm a huge geek. |
| 0:40.5 | I know a lot of our audience loves to dive deep into that science. |
| 0:44.4 | And I think with mitochondrial health, there's a lot of buzzwords out here. |
| 0:50.5 | And I know that timeline has a very unique approach to, you know, what you guys are really targeting with mitochondria. So before we dive into that, can you give us a little overview, maybe a 101 on like, |
| 0:56.7 | why do mitochondria matter? And what should we know on a very surface level about them? |
| 1:02.6 | Yeah, that's a really good question. So mitochondria, often, they are called the powerhouse of the |
| 1:09.5 | cell, which sometimes I think we are missing so many, |
| 1:13.3 | many things because I like to call her the CEO of the cells. |
| 1:17.9 | Basically, there was a lot of paper so recently calling that way. |
| 1:21.3 | And I think this is so true because, yes, they are known to produce so much, to help to produce |
| 1:26.8 | the energy, but they have |
| 1:28.3 | so multiple function and everything is interlinked. So I think that's what people reduce them |
| 1:35.4 | sometimes with this sentence, powerhouse of the cell, and for all the organ of our body, |
| 1:40.6 | they are so concerned and so helpful. And it was mostly seen for a disease perspective |
| 1:47.0 | before being a buzz, you know, like, because this word means so much to the researcher, |
| 1:53.3 | but when he came out to the public, saying, what is the mitochondria? People saying it's |
| 1:58.0 | battery, it's giving you energy, but he does so much more. |
| 2:02.4 | So that's why I think today is really out there to the public and we need to really detail |
| 2:08.0 | everything that this organ is doing. |
| 2:11.0 | Yeah, I mean, I love what you said, that it is so much more, and it's more like the CEO of |
... |
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