4.5 • 758 Ratings
🗓️ 5 September 2025
⏱️ 56 minutes
🧾️ Download transcript
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In this solo recap episode, Vanessa breaks down her in-depth interview with Dr. Andy Galpin, one of the world's leading muscle scientists and performance physiologists. This 60-minute masterclass distills the most important takeaways from their conversation into clear, actionable steps for fat loss, body recomposition, and metabolic health.
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The real science of fat loss — why stored fat leaves your body as exhaled carbon, not sweat.
Carbon in vs. carbon out — how to think about energy balance more clearly.
Why nutrition drives fat loss — the 90/10 rule of diet vs. exercise.
The two macros most women misjudge — why we consistently overestimate protein and underestimate fat.
What to do if you're stuck at 1,200 calories — Andy's three-step framework: reevaluate, build muscle, or take a structured diet break.
Protein timing truths — total daily protein matters more than timing, plus the role of pre-sleep protein.
Metabolic flexibility demystified — why it's about switching fuels efficiently, not always "burning fat."
The sleep–fat loss connection — how poor sleep alters hormones, cravings, and body composition.
Anabolic resistance and menopause — why blood flow and activity may matter more than hormones alone.
A one-week action blueprint — practical steps you can apply right away for better results.
This episode is packed with clarity and practical insights to help you optimize protein, training, and recovery so you can burn fat, preserve lean mass, and unlock your healthiest, strongest self.
Free high-protein keto guide: The Keto Reset eBook https://ketogenicgirl.com/pages/new-free-ebook
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Free high-protein keto guide: The Keto Reset eBook
👤 Connect with Vanessa:
• Instagram: @ketogenicgirl
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📱 Follow @ketogenicgirl for the latest studies and strategies on fat loss and protein optimization
📸 Follow @optimalproteinpodcast for episode visuals and updates
💬 Join the Facebook group: Optimal Protein Podcast Community
🎙 The content in this podcast is for informational purposes only and not medical advice. Always consult your healthcare provider before making major dietary or lifestyle changes.
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| 0:00.0 | Welcome to the Optimal Protein Podcast. I'm Vanessa Spina. Hello, my friends, and welcome back to the Optimal |
| 0:07.6 | Protein podcast. I'm your host, Vanessa, and today I'm bringing you a deep dive recap of my conversation |
| 0:14.1 | with the one and only Dr. Andy Galpin, a world-renowned muscle scientist and performance physiologist |
| 0:20.4 | so that you can walk away with |
| 0:22.4 | crystal clear practical strategies for fat loss and achieving the body recomposition that you want. |
| 0:30.1 | Now, in this solo breakdown episode, we're going to cover the true biochemistry of fat loss, |
| 0:35.9 | why fat loss is literally about exhaling carbons. And if you know me, |
| 0:41.1 | I was very geeked out about this part of the podcast with Dr. Galpin. Why nutrition, not exercise, |
| 0:47.2 | drives most fat loss, the two macros that people consistently misjudge when they're assessing |
| 0:53.8 | what they are eating. |
| 0:55.4 | And what to do if you're a woman who's been stuck at 1,200 calories for a long time and stalled out. |
| 1:01.6 | We're also going to talk about protein timing truths, including pre-sleep protein. |
| 1:06.2 | What metabolic flexibility actually means, as Dr. Galpin says, the definition has been misconstrued |
| 1:13.0 | on the internet quite a bit, and how sleep drives fat loss or fat gain, and finally, how to fight |
| 1:19.6 | anabolic resistance across pari menopause and beyond. So pull up a seat, grab your coffee |
| 1:25.9 | with collagen, or maybe a nice warm tea or maybe some water |
| 1:30.6 | with electrolytes, whatever you are sipping on. |
| 1:33.0 | I am so excited for this recap and I can't wait to jump into it. |
| 1:37.2 | We're going to get right into it after this quick break. |
| 1:41.3 | I want to tell you all about my new favorite protein bar that has become a household |
| 1:47.6 | staple for us. So the protein bars made by IQ Bar are so delicious that we call them protein |
| 1:54.8 | cookies. IQ Bar makes a protein-based snack that is made with brain-boasting nutrients to refuel, nourish, |
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